Buttermilk Biscuit and Sausage Casserole
A comforting casserole with flaky buttermilk biscuits, crispy sausage, and a creamy cheese sauce, ideal for a hearty family dinner. This american-inspired quick meals ready in about 55 minutes pairs (ground, 80% lean) sausage, milk, (grated) cheddar cheese for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 450 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.
Ingredients
- 8 (store-bought or homemade) buttermilk biscuits
- 1 lb (ground, 80% lean) sausage
- 1 cup milk
- 1 cup (grated) cheddar cheese
- 2 tbsp flour
- 2 tbsp butter
- 1/2 tsp salt
- 1/4 tsp black pepper
- 1/4 tsp cayenne pepper
Instructions
- Step 1: Preheat oven to 400°F (200°C). In a large skillet, cook 1 lb ground sausage over medium heat until browned and crumbly, about 8-10 minutes. Drain excess fat and set aside.
- Step 2: In a saucepan, melt 2 tbsp butter over medium heat. Whisk in 2 tbsp flour, 1/2 tsp salt, 1/4 tsp black pepper, and 1/4 tsp cayenne. Cook for 1-2 minutes until the mixture is bubbly and golden.
- Step 3: Gradually stir in 1 cup milk, whisking constantly until the sauce is smooth and thick. Reduce heat to low and stir in 1 cup grated cheddar cheese until melted and the sauce is glossy.
- Step 4: Layer 8 buttermilk biscuits in a 9x13-inch baking dish. Top with the cooked sausage and pour the cheese sauce over everything. Bake for 20-25 minutes until the biscuits are golden and the sauce is bubbling. Let cool for 5 minutes before serving.
Equipment for this recipe
Top-rated tools to make this recipe successfully.
Frequently asked questions
How long does Buttermilk Biscuit and Sausage Casserole take to make?
Total time is about 55 minutes (30 min prep + 25 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.
How do I store leftover Buttermilk Biscuit and Sausage Casserole?
Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep (ground, 80% lean) sausage from drying out.
Can I substitute ingredients in Buttermilk Biscuit and Sausage Casserole?
Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.
How do I scale Buttermilk Biscuit and Sausage Casserole for a different number of people?
The recipe is written for 6 servings. Multiply each ingredient by (your serving target / 6). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.
What goes well with Buttermilk Biscuit and Sausage Casserole?
American quick meals like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.
What others are saying
- ★★★★★
Simple and delicious.
- ★★★★★
The flavors in this buttermilk are incredible.
- ★★★★☆
Nice recipe! Presentation was beautiful. Flavor was good, not great.