Deep-Dish Chicago-Style Sausage and Pepperoni Pizza

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

A hearty deep-dish pizza loaded with Italian sausage, pepperoni, and mozzarella cheese baked in a buttery crust for a true Chicago pizza experience. This american-inspired pizza ready in about 50 minutes pairs (store-bought or homemade) pizza dough, Italian sausage, casing removed, pepperoni slices for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 480 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 20 min Cook: 30 min Serves 6 American cuisine 480 cal/serving
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Ingredients

Instructions

  1. Step 1: Preheat oven to 425°F. Roll out 1 lb pizza dough into a 12-inch circle and press into a deep 9-inch round pan, pushing dough up the sides to form a deep crust.
  2. Step 2: Heat 2 tbsp olive oil in a skillet over medium heat. Add 8 oz Italian sausage (removed from casing) and cook, breaking up with a spoon, for 5-6 minutes until browned and cooked through.
  3. Step 3: Stir in 2 minced garlic cloves, 1 tsp dried oregano, 1 tsp salt, and 1/2 tsp black pepper; cook for 1 minute until fragrant. Remove from heat.
  4. Step 4: Layer 1 cup shredded mozzarella cheese evenly over the dough. Scatter cooked sausage and 1/2 cup pepperoni slices on top.
  5. Step 5: Spread 1 1/2 cups crushed tomatoes evenly over the toppings, then sprinkle 1/4 cup grated Parmesan cheese on top.
  6. Step 6: Bake for 25-30 minutes until crust is golden brown and cheese is bubbly. Let cool for 5 minutes before slicing and serving.

Equipment for this recipe

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Frequently asked questions

How long does Deep-Dish Chicago-Style Sausage and Pepperoni Pizza take to make?

Total time is about 50 minutes (20 min prep + 30 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Deep-Dish Chicago-Style Sausage and Pepperoni Pizza?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep pepperoni slices from drying out.

Can I substitute ingredients in Deep-Dish Chicago-Style Sausage and Pepperoni Pizza?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Deep-Dish Chicago-Style Sausage and Pepperoni Pizza for a different number of people?

The recipe is written for 6 servings. Multiply each ingredient by (your serving target / 6). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Deep-Dish Chicago-Style Sausage and Pepperoni Pizza?

American pizza like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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