Grilled Lemon-Oregano Chicken with Tzatziki Sauce

By Lauren Mitchell, Test Kitchen Director · Reviewed by AislePrompt Editorial · Published 2026-04-25 · Updated 2026-04-25

Juicy chicken marinated in fresh lemon juice and oregano, grilled to perfection, and served with a cooling cucumber-yogurt tzatziki sauce. This mediterranean-inspired greek ready in about 27 minutes blends pounds boneless skinless chicken thighs, fresh lemon juice, extra virgin olive oil into a versatile sauce that lifts everything from grain bowls and roasted vegetables to grilled proteins — a small-batch staple worth keeping in the fridge. Each serving lands at about 320 calories and feeds 4, so a small batch covers several meals across the week without taking over the fridge. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Ingredients

• 1.5 pounds boneless skinless chicken thighs
• 1/4 cup fresh lemon juice
• 3 tbsp extra virgin olive oil
• 2 tsp dried oregano
• 3 cloves garlic cloves, minced
• 1 tsp salt
• 1/2 tsp black pepper
• 1 cup Greek yogurt
• 1/2 medium cucumber, grated and drained
• 2 tbsp fresh dill, chopped
• 1 tbsp white wine vinegar
• 1 clove garlic clove, minced (for tzatziki)
• 1/2 tsp salt (for tzatziki)

Instructions

1. Step 1: In a medium bowl, combine 1.5 pounds boneless skinless chicken thighs, 1/4 cup fresh lemon juice, 3 tbsp extra virgin olive oil, 2 tsp dried oregano, 3 minced garlic cloves, 1 tsp salt, and 1/2 tsp black pepper. Toss well to coat and marinate in the refrigerator for at least 45 minutes, up to 2 hours.
2. Step 2: Meanwhile, prepare the tzatziki sauce by mixing 1 cup Greek yogurt, 1/2 grated and well-drained cucumber, 2 tbsp chopped fresh dill, 1 tbsp white wine vinegar, 1 minced garlic clove, and 1/2 tsp salt in a bowl. Stir until smooth and refrigerate until ready to serve.
3. Step 3: Preheat the grill to medium-high heat (about 400°F). Remove chicken from marinade and grill for 5-6 minutes on each side, until the internal temperature reaches 165°F and the surface has light grill marks.
4. Step 4: Transfer chicken to a plate and rest for 5 minutes before slicing. Serve warm with a generous dollop of the prepared tzatziki sauce alongside.