Mediterranean Vegetable Lasagna

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

A vibrant lasagna layered with roasted Mediterranean vegetables and creamy béchamel. This mediterranean-inspired pasta (vegetarian) ready in about 75 minutes pairs sheets, no-boil lasagna noodles, olive oil, divided salt for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 420 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 25 min Cook: 50 min Serves 6 Mediterranean cuisine 420 cal/serving
Build a week of meals around this recipe → Shop this recipe on Instacart → Shop equipment ↓

Ingredients

Equipment for this recipe

Top-rated tools to make this recipe successfully.

More Bakeware & baking tools → Shop all kitchen tools →

Instructions

  1. Step 1: Preheat oven to 425°F. Toss 1 medium sliced eggplant, 2 medium sliced zucchinis, and 1 large sliced red bell pepper with 3 tbsp olive oil, 1 tsp salt, and 1/2 tsp black pepper. Arrange on baking sheets and roast for 20 minutes until tender and slightly caramelized.
  2. Step 2: Meanwhile, melt 4 tbsp unsalted butter in a medium saucepan over medium heat. Add 3 minced garlic cloves and sauté for 1 minute until fragrant. Stir in 4 tbsp all-purpose flour and cook, whisking constantly, for 2 minutes to form a roux.
  3. Step 3: Gradually whisk in 3 cups warmed whole milk and cook for 5-7 minutes, stirring frequently, until the béchamel sauce thickens and coats the back of a spoon. Remove from heat and stir in 1/2 cup grated Parmesan cheese and 1/4 tsp salt.
  4. Step 4: In a 9x13 inch baking dish, spread a thin layer of béchamel sauce, then layer 3 lasagna noodles (no-boil), half the roasted vegetables, 1/2 cup béchamel, 3/4 cup shredded mozzarella, and sprinkle with 1/8 tsp black pepper and 2 tbsp chopped fresh basil. Repeat layers twice more to create four layers, finishing with noodles topped by béchamel, remaining mozzarella, and 1/4 cup Parmesan cheese.
  5. Step 5: Cover with foil and bake at 375°F for 30 minutes. Remove foil and bake for another 10 minutes until bubbly and golden on top. Let rest for 10 minutes before serving.

Frequently asked questions

How long does Mediterranean Vegetable Lasagna take to make?

Total time is about 75 minutes (25 min prep + 50 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Mediterranean Vegetable Lasagna?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep olive oil from drying out.

Can I substitute ingredients in Mediterranean Vegetable Lasagna?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Mediterranean Vegetable Lasagna for a different number of people?

The recipe is written for 6 servings. Multiply each ingredient by (your serving target / 6). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

Is Mediterranean Vegetable Lasagna vegetarian?

Yes — this recipe is tagged vegetarian based on its ingredient list. Always cross-check labels for packaged ingredients (sauces, broths, condiments) since formulations vary by brand.