Sautéed Chicken Enchiladas with Red Chili Sauce

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Sautéed shredded chicken wrapped in corn tortillas, smothered in a rich homemade red chili sauce and baked with melted cheese for a comforting Cinco de Mayo entrée. This Mexican-inspired Cinco de Mayo recipe, ready in about 80 minutes, pairs boneless skinless chicken breasts, olive oil, yellow onion for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 480 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 30 min Cook: 50 min Serves 6 Mexican cuisine 480 cal/serving
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Ingredients

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Instructions

  1. Step 1: Place 4 dried guajillo chilies and 2 dried ancho chilies in a medium pot and cover with 2 cups vegetable broth. Bring to a simmer and cook for 15 minutes until chilies soften.
  2. Step 2: Blend softened chilies and broth until smooth to make red chili sauce; set aside.
  3. Step 3: Heat 1 tbsp olive oil in a large skillet over medium heat. Add 2 boneless skinless chicken breasts and cook for 6-7 minutes per side until cooked through. Remove, shred with two forks.
  4. Step 4: In the same skillet, add 2 tbsp olive oil and 1 small diced yellow onion, sauté for 4 minutes until translucent. Add 3 minced garlic cloves, 1 tsp ground cumin, 1/2 tsp dried oregano, 1/4 tsp black pepper, and 1/2 tsp salt, cooking for 1 minute until fragrant.
  5. Step 5: Stir shredded chicken into the onion mixture and 1 cup of the prepared red chili sauce, heating for 3 minutes until combined.
  6. Step 6: Preheat oven to 375°F. Lightly grease a 9x13-inch baking dish.
  7. Step 7: Warm 12 corn tortillas to make pliable. Spoon about 1/3 cup chicken filling onto each tortilla, roll tightly, and place seam side down in the baking dish.
  8. Step 8: Pour remaining red chili sauce evenly over the enchiladas and top with 2 cups shredded Monterey Jack cheese and remaining 3/4 tsp salt.
  9. Step 9: Bake for 20 minutes until cheese is melted and bubbly. Garnish with 1/4 cup chopped fresh cilantro before serving.

Frequently asked questions

How long does Sautéed Chicken Enchiladas with Red Chili Sauce take to make?

Total time is about 80 minutes (30 min prep + 50 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Sautéed Chicken Enchiladas with Red Chili Sauce?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep olive oil from drying out.

Can I substitute ingredients in Sautéed Chicken Enchiladas with Red Chili Sauce?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Sautéed Chicken Enchiladas with Red Chili Sauce for a different number of people?

The recipe is written for 6 servings. Multiply each ingredient by (your serving target / 6). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Sautéed Chicken Enchiladas with Red Chili Sauce?

Mexican cinco de mayo like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.