Slow-Cooked Beef Barbacoa with Chipotle and Guajillo Chilies

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Rich and tender shredded beef slow-cooked in a smoky, spicy sauce made from chipotle and guajillo chilies, perfect for tacos, burritos, or bowls. This mexican-inspired cinco de mayo ready in about 510 minutes pairs beef chuck roast, dried guajillo chilies, dried chipotle chilies for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 520 calories and feeds 8, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

★ 4.6 (9 ratings) Prep: 30 min Cook: 480 min Serves 8 Mexican cuisine 520 cal/serving
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Ingredients

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Instructions

  1. Step 1: Remove stems and seeds from 4 guajillo and 2 chipotle dried chilies. Toast them in a dry skillet over medium heat for 1-2 minutes until fragrant. Transfer to a bowl and cover with hot water for 20 minutes to soften.
  2. Step 2: Drain chilies and blend with 1 large quartered white onion, 6 garlic cloves, 2 cups beef broth, and 2 tbsp apple cider vinegar until smooth.
  3. Step 3: Heat 2 tbsp vegetable oil in a large skillet over medium-high heat. Season 3 lbs beef chuck roast chunks with 2 tsp salt and 1 tsp black pepper. Brown beef in batches for 3-4 minutes per side until deeply browned. Transfer to slow cooker.
  4. Step 4: Pour chili sauce over beef in the slow cooker. Add 1 tbsp ground cumin, 1 tsp dried oregano, and 2 bay leaves.
  5. Step 5: Cook on low for 8 hours or on high for 5 hours until beef is very tender and shreds easily.
  6. Step 6: Remove bay leaves and shred beef with two forks directly in the sauce. Stir to combine.
  7. Step 7: Serve hot with chopped 1/4 cup fresh cilantro and lime wedges for squeezing over.

Frequently asked questions

How long does Slow-Cooked Beef Barbacoa with Chipotle and Guajillo Chilies take to make?

Total time is about 510 minutes (30 min prep + 480 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Slow-Cooked Beef Barbacoa with Chipotle and Guajillo Chilies?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep beef chuck roast from drying out.

Can I substitute ingredients in Slow-Cooked Beef Barbacoa with Chipotle and Guajillo Chilies?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Slow-Cooked Beef Barbacoa with Chipotle and Guajillo Chilies for a different number of people?

The recipe is written for 8 servings. Multiply each ingredient by (your serving target / 8). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Slow-Cooked Beef Barbacoa with Chipotle and Guajillo Chilies?

Mexican cinco de mayo like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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