Slow-Smoked Brisket with Mustard No. 2 Glaze

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

A classic slow-smoked beef brisket finished with a sweet and mildly spicy mustard glaze inspired by the Southern BBQ tradition. This beef recipe, ready in about 540 minutes, pairs beef brisket, kosher salt, black pepper for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 600 calories and feeds 8, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 60 min Cook: 480 min Serves 8 600 cal/serving
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Ingredients

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Instructions

  1. Step 1: Mix 2 tbsp kosher salt, 2 tbsp black pepper, 1 tbsp smoked paprika, and 1 tbsp garlic powder in a bowl and rub evenly over all sides of 5 lbs beef brisket. Let rest uncovered in the refrigerator for at least 4 hours or overnight.
  2. Step 2: Preheat smoker to 225°F and place the brisket fat side up on the smoker grate. Smoke for 6 hours maintaining a steady temperature and smoke.
  3. Step 3: In a small bowl, whisk together 1/4 cup yellow mustard, 2 tbsp honey, 1 tbsp apple cider vinegar, and 1 tsp hot sauce to make the Mustard No. 2 glaze.
  4. Step 4: After 6 hours, brush the mustard glaze evenly over the brisket and continue smoking for an additional 2 hours, or until the internal temperature reaches 200°F and the glaze is set.
  5. Step 5: Remove brisket from smoker and wrap in butcher paper, resting for 1 hour before slicing thinly against the grain to serve.

Frequently asked questions

How long does Slow-Smoked Brisket with Mustard No. 2 Glaze take to make?

Total time is about 540 minutes (60 min prep + 480 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Slow-Smoked Brisket with Mustard No. 2 Glaze?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep beef brisket from drying out.

Can I substitute ingredients in Slow-Smoked Brisket with Mustard No. 2 Glaze?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Slow-Smoked Brisket with Mustard No. 2 Glaze for a different number of people?

The recipe is written for 8 servings. Multiply each ingredient by (your serving target / 8). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Slow-Smoked Brisket with Mustard No. 2 Glaze?

BBQ & Smoked beef like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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