Spiced Cajun Po'Boy Sandwich with Remoulade Sauce

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

A classic New Orleans po'boy sandwich filled with crispy spiced fried shrimp and tangy remoulade sauce on a crusty French roll. This Creole-inspired sandwich and wrap recipe, ready in about 35 minutes, pairs Medium shrimp, peeled and deveined, Cajun seasoning, All-purpose flour for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 550 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 20 min Cook: 15 min Serves 4 Creole cuisine 550 cal/serving
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Ingredients

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Instructions

  1. Step 1: In a large bowl, toss 1 lb medium peeled shrimp with 2 tbsp Cajun seasoning until evenly coated.
  2. Step 2: Pour 1 cup buttermilk into a separate bowl. Place 1 cup all-purpose flour in another shallow dish.
  3. Step 3: Dip each shrimp first into the buttermilk, then dredge in flour, shaking off excess.
  4. Step 4: Heat 4 cups vegetable oil in a deep skillet or fryer to 350°F. Fry shrimp in batches for 2-3 minutes until golden brown and crispy. Drain on paper towels.
  5. Step 5: To make remoulade sauce, whisk together 1/2 cup mayonnaise, 1 tbsp Dijon mustard, 1 tsp horseradish, 1 tsp Worcestershire sauce, 1 tsp hot sauce, 1 tbsp lemon juice, 1 tbsp chopped parsley, 1 tsp salt, and 1/2 tsp black pepper until smooth.
  6. Step 6: Slice 4 French bread rolls lengthwise without cutting all the way through. Spread remoulade sauce generously inside each roll.
  7. Step 7: Layer with 1 cup shredded lettuce, 1 cup sliced tomatoes, and the fried shrimp. Serve immediately.

Frequently asked questions

How long does Spiced Cajun Po'Boy Sandwich with Remoulade Sauce take to make?

Total time is about 35 minutes (20 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Spiced Cajun Po'Boy Sandwich with Remoulade Sauce?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep cajun seasoning from drying out.

Can I substitute ingredients in Spiced Cajun Po'Boy Sandwich with Remoulade Sauce?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Spiced Cajun Po'Boy Sandwich with Remoulade Sauce for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Spiced Cajun Po'Boy Sandwich with Remoulade Sauce?

Creole sandwiches & wraps like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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