Vodka-Infused Penne alla Vodka with Tomato Cream Sauce

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

A smooth tomato cream sauce elevated with vodka, tossed with tender penne pasta and finished with fresh basil and Parmesan. This italian-inspired pasta ready in about 35 minutes pairs penne pasta, extra virgin olive oil, small, finely diced yellow onion for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 480 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart.

Prep: 10 min Cook: 25 min Serves 4 Italian cuisine 480 cal/serving
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Ingredients

Instructions

  1. Step 1: Bring a large pot of salted water to a boil. Add 12 oz penne pasta and cook for 10-12 minutes until al dente, then drain and reserve 1/2 cup pasta water.
  2. Step 2: Heat 2 tbsp extra virgin olive oil in a deep skillet over medium heat. Add 1 small finely diced yellow onion and sauté for 5 minutes until translucent.
  3. Step 3: Add 4 minced garlic cloves and 1/4 tsp red pepper flakes, cooking for 30 seconds until fragrant.
  4. Step 4: Pour in 1/3 cup vodka and cook for 3 minutes, allowing the alcohol to reduce slightly.
  5. Step 5: Add 28 oz crushed tomatoes and bring to a simmer. Cook for 10 minutes until the sauce thickens.
  6. Step 6: Stir in 3/4 cup heavy cream, season with salt and black pepper to taste, and cook for another 2 minutes to combine flavors.
  7. Step 7: Toss the drained penne pasta into the sauce along with 1/2 cup freshly grated Parmesan cheese and 1/4 cup chopped fresh basil. Add reserved pasta water 2 tbsp at a time if the sauce needs loosening. Serve warm.

Frequently asked questions

How long does Vodka-Infused Penne alla Vodka with Tomato Cream Sauce take to make?

Total time is about 35 minutes (10 min prep + 25 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Vodka-Infused Penne alla Vodka with Tomato Cream Sauce?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep penne pasta from drying out.

Can I substitute ingredients in Vodka-Infused Penne alla Vodka with Tomato Cream Sauce?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Vodka-Infused Penne alla Vodka with Tomato Cream Sauce for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Vodka-Infused Penne alla Vodka with Tomato Cream Sauce?

Italian pasta like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.