Vodka-Infused Spicy Tomato Penne Pasta

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Al dente penne pasta tossed in a spicy tomato cream sauce enriched with vodka and fresh basil. This italian-inspired pasta ready in about 35 minutes pairs penne pasta, for pasta water salt, extra virgin olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 480 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 25 min Serves 4 Italian cuisine 480 cal/serving
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Ingredients

Instructions

  1. Step 1: Bring a large pot of water to a rolling boil and add 1 tbsp salt. Add 12 oz penne pasta and cook for 10-12 minutes until al dente, then drain and reserve 1/2 cup pasta water.
  2. Step 2: While pasta cooks, heat 2 tbsp extra virgin olive oil in a large skillet over medium heat. Add 4 cloves minced garlic and 1/2 tsp red pepper flakes, sautéing for 1 minute until fragrant but not browned.
  3. Step 3: Pour in 28 oz crushed canned tomatoes and bring to a simmer. Cook for 10 minutes, stirring occasionally.
  4. Step 4: Add 1/4 cup vodka to the tomato sauce and simmer for 5 minutes to cook off the alcohol and deepen flavor.
  5. Step 5: Stir in 1/2 cup heavy cream and 1/4 cup chopped fresh basil leaves. Let the sauce cook for another 3 minutes until slightly thickened.
  6. Step 6: Add the drained penne pasta to the sauce along with 1/2 cup grated Parmesan cheese and 1/4 cup reserved pasta water. Toss everything together over low heat until the sauce coats the pasta evenly. Season with black pepper to taste and serve warm.

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Frequently asked questions

How long does Vodka-Infused Spicy Tomato Penne Pasta take to make?

Total time is about 35 minutes (10 min prep + 25 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Vodka-Infused Spicy Tomato Penne Pasta?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep penne pasta from drying out.

Can I substitute ingredients in Vodka-Infused Spicy Tomato Penne Pasta?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Vodka-Infused Spicy Tomato Penne Pasta for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Vodka-Infused Spicy Tomato Penne Pasta?

Italian pasta like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.