Baked Cajun-Spiced Salmon with Citrus Butter

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

Juicy salmon fillets coated in a smoky Cajun spice blend, baked to perfection and topped with a luscious citrus butter for a flavorful seafood delight. This caribbean-inspired seafood ready in about 25 minutes pairs fillets (6 oz each) salmon fillets, Cajun seasoning, softened unsalted butter for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 400 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 15 min Serves 4 Caribbean cuisine 400 cal/serving
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Ingredients

Instructions

  1. Step 1: Preheat oven to 400°F. Pat dry 4 salmon fillets (6 oz each) and brush with 1 tbsp olive oil.
  2. Step 2: Evenly sprinkle 2 tbsp Cajun seasoning over the salmon, pressing gently to adhere.
  3. Step 3: Place fillets on a lined baking sheet and bake for 12-15 minutes until salmon flakes easily with a fork.
  4. Step 4: While salmon bakes, mix 4 tbsp softened unsalted butter with 1 tsp lemon zest, 1 tsp orange zest, 1 tbsp fresh lemon juice, 1 tbsp fresh orange juice, 1/2 tsp salt, and 1/4 tsp black pepper until smooth.
  5. Step 5: Remove salmon from oven and immediately dollop the citrus butter on top of each fillet, allowing it to melt and infuse the fish with bright flavors.
  6. Step 6: Serve warm with your choice of sides.

Equipment for this recipe

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Frequently asked questions

How long does Baked Cajun-Spiced Salmon with Citrus Butter take to make?

Total time is about 25 minutes (10 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Baked Cajun-Spiced Salmon with Citrus Butter?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep cajun seasoning from drying out.

Can I substitute ingredients in Baked Cajun-Spiced Salmon with Citrus Butter?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Baked Cajun-Spiced Salmon with Citrus Butter for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Baked Cajun-Spiced Salmon with Citrus Butter?

Caribbean seafood like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.