Cajun-Spiced Shrimp Po’Boy Sandwich
A lively sandwich featuring spicy Cajun-seasoned shrimp nestled in a crusty French roll with crisp lettuce and tangy remoulade sauce. This southern-inspired sandwiches & wraps ready in about 25 minutes pairs large shrimp, peeled and deveined, Cajun seasoning, all-purpose flour for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 550 calories and feeds 2, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.
Ingredients
- 12 pieces large shrimp, peeled and deveined
- 2 tbsp Cajun seasoning
- 1/2 cup all-purpose flour
- 1/2 cup buttermilk
- 1 cup vegetable oil
- 2 French rolls
- 1 cup shredded iceberg lettuce
- 1 medium ripe tomato, sliced
- 1/3 cup mayonnaise
- 1 tbsp Dijon mustard
- 1 tsp hot sauce
- 1 tsp lemon juice
- 1/4 tsp salt
- 1/4 tsp black pepper
Instructions
- Step 1: In a medium bowl, combine 1/2 cup all-purpose flour and 2 tbsp Cajun seasoning. In another bowl, pour 1/2 cup buttermilk. Dip each of the 12 large shrimp first into the buttermilk, then dredge in the seasoned flour, coating evenly.
- Step 2: Heat 1 cup vegetable oil in a deep skillet over medium-high heat until it reaches 350°F. Carefully fry the coated shrimp in batches for 2-3 minutes until golden and crispy, then transfer to a paper towel-lined plate to drain.
- Step 3: In a small bowl, whisk together 1/3 cup mayonnaise, 1 tbsp Dijon mustard, 1 tsp hot sauce, 1 tsp lemon juice, 1/4 tsp salt, and 1/4 tsp black pepper until smooth to create the remoulade sauce.
- Step 4: Slice 2 French rolls lengthwise without cutting all the way through. Spread a generous layer of remoulade sauce inside each roll. Layer 1/2 cup shredded iceberg lettuce and 3-4 tomato slices evenly on each.
- Step 5: Arrange 6 fried shrimp inside each roll over the lettuce and tomato. Close the sandwich and press gently. Serve immediately while shrimp are crispy and warm.
Equipment for this recipe
Top-rated tools to make this recipe successfully.
Frequently asked questions
How long does Cajun-Spiced Shrimp Po’Boy Sandwich take to make?
Total time is about 25 minutes (15 min prep + 10 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.
How do I store leftover Cajun-Spiced Shrimp Po’Boy Sandwich?
Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep cajun seasoning from drying out.
Can I substitute ingredients in Cajun-Spiced Shrimp Po’Boy Sandwich?
Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.
How do I scale Cajun-Spiced Shrimp Po’Boy Sandwich for a different number of people?
The recipe is written for 2 servings. Multiply each ingredient by (your serving target / 2). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.
What goes well with Cajun-Spiced Shrimp Po’Boy Sandwich?
Southern sandwiches & wraps like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.
