Deep-Dish Pepperoni and Mushroom Pizza with Three Cheese Blend

By · Reviewed by AislePrompt Editorial · ·

A hearty deep-dish pizza loaded with spicy pepperoni, earthy mushrooms, and a rich blend of mozzarella, Parmesan, and cheddar cheeses. This italian-inspired pizza ready in about 130 minutes pairs all-purpose flour, active dry yeast, warm water (110°F/43°C) for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 700 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 100 min Cook: 30 min Serves 4 Italian cuisine 700 cal/serving
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Ingredients

Instructions

  1. Step 1: In a bowl, mix 300 g all-purpose flour, 3 g active dry yeast, 1 tsp salt, 2 tbsp olive oil, and 180 ml warm water (110°F/43°C). Knead for 10 minutes until soft and elastic. Cover and let rise for 1.5 hours until doubled.
  2. Step 2: Preheat oven to 425°F (220°C). Grease a 9-inch deep-dish pan with olive oil.
  3. Step 3: Press the risen dough into the pan, pushing it up the sides to form a thick crust.
  4. Step 4: Spread 150 g tomato sauce evenly over the dough base.
  5. Step 5: Layer 100 g sliced pepperoni and 80 g sliced mushrooms evenly over the sauce.
  6. Step 6: Combine 100 g shredded mozzarella, 30 g grated Parmesan, and 50 g shredded sharp cheddar, then sprinkle the cheese blend evenly on top.
  7. Step 7: Bake for 25-30 minutes until the crust is golden and cheese is bubbly and browned in spots.
  8. Step 8: Remove from oven and let rest 5 minutes before slicing and serving.

Equipment for this recipe

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Frequently asked questions

How long does Deep-Dish Pepperoni and Mushroom Pizza with Three Cheese Blend take to make?

Total time is about 130 minutes (100 min prep + 30 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Deep-Dish Pepperoni and Mushroom Pizza with Three Cheese Blend?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep all-purpose flour from drying out.

Can I substitute ingredients in Deep-Dish Pepperoni and Mushroom Pizza with Three Cheese Blend?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Deep-Dish Pepperoni and Mushroom Pizza with Three Cheese Blend for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Deep-Dish Pepperoni and Mushroom Pizza with Three Cheese Blend?

Italian pizza like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.