Deep-Dish Sausage and Pepperoni Chicago-Style Pizza

By · Reviewed by AislePrompt Editorial · ·

A hearty Chicago deep-dish pizza layered with spicy Italian sausage, pepperoni, and a robust tomato sauce baked to golden perfection. This italian-inspired pizza ready in about 70 minutes pairs all-purpose flour, active dry yeast, 110°F warm water for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 520 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 20 min Cook: 50 min Serves 6 Italian cuisine 520 cal/serving
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Ingredients

Instructions

  1. Step 1: In a small bowl, dissolve 2 1/4 tsp active dry yeast and 1 tbsp sugar in 1 cup warm water (110°F). Let sit for 5 minutes until foamy.
  2. Step 2: In a large bowl, combine 3 cups all-purpose flour and 1 tsp salt. Add the yeast mixture and 1/4 cup olive oil, stirring until a dough forms. Knead on a floured surface for 8 minutes until smooth and elastic.
  3. Step 3: Place dough in an oiled bowl, cover with a damp towel, and let rise in a warm place for 1 hour until doubled in size.
  4. Step 4: Meanwhile, cook 8 oz Italian sausage over medium heat in a skillet, breaking it into crumbles until browned and cooked through, about 6 minutes. Remove and set aside.
  5. Step 5: In the same skillet, add 3 minced garlic cloves and sauté for 30 seconds until fragrant. Add 2 cups crushed tomatoes, 1 tsp dried oregano, 1/4 tsp red pepper flakes, and simmer on low for 15 minutes until thickened.
  6. Step 6: Preheat oven to 425°F. Punch down dough and press it into a well-oiled 12-inch deep-dish pizza pan, pulling dough slightly up the sides.
  7. Step 7: Layer the crust with 3 cups shredded mozzarella cheese, then spread the cooked sausage evenly, followed by 1 cup pepperoni slices.
  8. Step 8: Pour the tomato sauce evenly over the toppings and sprinkle 1/4 cup grated Parmesan cheese on top.
  9. Step 9: Bake for 30-35 minutes until crust is golden and cheese is bubbly. Remove from oven and scatter 1/4 cup chopped fresh basil over the top before slicing and serving.

Equipment for this recipe

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Frequently asked questions

How long does Deep-Dish Sausage and Pepperoni Chicago-Style Pizza take to make?

Total time is about 70 minutes (20 min prep + 50 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Deep-Dish Sausage and Pepperoni Chicago-Style Pizza?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep all-purpose flour from drying out.

Can I substitute ingredients in Deep-Dish Sausage and Pepperoni Chicago-Style Pizza?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Deep-Dish Sausage and Pepperoni Chicago-Style Pizza for a different number of people?

The recipe is written for 6 servings. Multiply each ingredient by (your serving target / 6). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Deep-Dish Sausage and Pepperoni Chicago-Style Pizza?

Italian pizza like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.