Grilled Gyro-Spiced Chicken with Tzatziki and Warm Pita

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

Tender chicken marinated in classic Mediterranean gyro spices, grilled and served with refreshing tzatziki sauce and warm pita bread for a flavorful handheld meal. This mediterranean-inspired chicken (mediterranean) ready in about 27 minutes pairs boneless skinless chicken thighs, Greek yogurt, olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 350 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 12 min Serves 4 Mediterranean cuisine 350 cal/serving
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Ingredients

Instructions

  1. Step 1: In a medium bowl, combine 1/2 cup Greek yogurt, 3 tbsp olive oil, 3 minced garlic cloves, 1 tbsp dried oregano, 1 tsp ground cumin, 1 tsp ground coriander, 1 tsp paprika, 2 tbsp lemon juice, 1 tsp salt, and 1/2 tsp black pepper. Whisk until smooth. Add 1 lb boneless skinless chicken thighs and toss to coat evenly. Cover and marinate in the refrigerator for at least 1 hour or up to 4 hours.
  2. Step 2: Meanwhile, prepare tzatziki by mixing 1/2 cup plain Greek yogurt, 1/2 cup grated and drained cucumber, 2 tbsp chopped fresh dill, 1 minced garlic clove, and 1 tsp white vinegar in a small bowl. Stir and refrigerate to let flavors meld.
  3. Step 3: Preheat grill or grill pan to medium-high heat (around 400°F). Remove chicken from marinade and grill for 5-6 minutes per side until internal temperature reaches 165°F and edges develop a light char.
  4. Step 4: Warm 4 pita breads wrapped in foil on the grill for 2-3 minutes until soft and pliable.
  5. Step 5: Slice grilled chicken into strips, then assemble by placing chicken on each pita and topping with 2 tbsp of tzatziki sauce. Serve immediately.

Equipment for this recipe

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Frequently asked questions

How long does Grilled Gyro-Spiced Chicken with Tzatziki and Warm Pita take to make?

Total time is about 27 minutes (15 min prep + 12 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Grilled Gyro-Spiced Chicken with Tzatziki and Warm Pita?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep greek yogurt from drying out.

Can I substitute ingredients in Grilled Gyro-Spiced Chicken with Tzatziki and Warm Pita?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Grilled Gyro-Spiced Chicken with Tzatziki and Warm Pita for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Grilled Gyro-Spiced Chicken with Tzatziki and Warm Pita?

Mediterranean chicken like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.