Grilled Gyro-Spiced Chicken with Tzatziki Sauce

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Juicy grilled chicken marinated in traditional gyro spices served with a refreshing cucumber-yogurt tzatziki sauce. This mediterranean-inspired chicken (gluten free) ready in about 27 minutes blends boneless skinless chicken thighs, Greek yogurt, olive oil into a versatile sauce that lifts everything from grain bowls and roasted vegetables to grilled proteins — a small-batch staple worth keeping in the fridge. Each serving lands at about 320 calories and feeds 4, so a small batch covers several meals across the week without taking over the fridge. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 12 min Serves 4 Mediterranean cuisine 320 cal/serving
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Ingredients

Instructions

  1. Step 1: In a medium bowl, whisk together 1/4 cup Greek yogurt, 2 tbsp olive oil, 3 minced garlic cloves, 1 tbsp dried oregano, 1 tsp ground cumin, 1 tsp ground coriander, 1 tsp paprika, 1/4 tsp ground cinnamon, 2 tbsp lemon juice, 1 tsp salt, and 1/2 tsp black pepper to create the marinade. Add 1 lb boneless skinless chicken thighs, coating well. Cover and marinate for at least 1 hour in the refrigerator.
  2. Step 2: Preheat grill or grill pan to medium-high heat (about 400°F). Grill the marinated chicken thighs for 5-6 minutes per side until cooked through and nicely charred. Remove and let rest for 5 minutes.
  3. Step 3: While chicken rests, prepare tzatziki sauce by combining 1/2 cup grated and drained cucumber, 1/4 cup Greek yogurt, 1 tbsp fresh chopped dill, 1 tsp white vinegar, 1 tbsp fresh lemon juice, and 1/4 tsp salt in a bowl. Mix well and refrigerate until serving.
  4. Step 4: Slice grilled chicken into strips and serve with chilled tzatziki sauce alongside warm pita bread or salad greens.

Equipment for this recipe

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Frequently asked questions

How long does Grilled Gyro-Spiced Chicken with Tzatziki Sauce take to make?

Total time is about 27 minutes (15 min prep + 12 min cook). A small batch typically covers several meals in the week — store as the recipe directs.

How do I store leftover Grilled Gyro-Spiced Chicken with Tzatziki Sauce?

Transfer to an airtight jar and refrigerate for up to 5–7 days. Most sauces freeze well for up to 2 months — portion into small containers or freezer bags so you can thaw only what you need. Stir before serving; cream- or yogurt-based sauces may separate on standing.

Can I substitute ingredients in Grilled Gyro-Spiced Chicken with Tzatziki Sauce?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Grilled Gyro-Spiced Chicken with Tzatziki Sauce for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

Is Grilled Gyro-Spiced Chicken with Tzatziki Sauce gluten free?

Yes — this recipe is tagged gluten free based on its ingredient list. Always cross-check labels for packaged ingredients (sauces, broths, condiments) since formulations vary by brand.