Lazy Bubble Up Pizza Casserole
A fun, layered casserole that bubbles up cheesy tomato sauce and pepperoni over soft biscuit dough for an effortless pizza night. This italian-inspired comfort food ready in about 40 minutes pairs (1 tube) refrigerated biscuit dough, pepperoni slices, shredded mozzarella cheese for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 620 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.
Ingredients
- 16 oz (1 tube) refrigerated biscuit dough
- 1 cup pepperoni slices
- 2 cups shredded mozzarella cheese
- 1 1/2 cups pizza sauce
- 1 tbsp olive oil
- 1 tsp dried Italian seasoning
- 1/4 cup grated parmesan cheese
- 2 tbsp chopped (optional) fresh basil
Equipment for this recipe
Top-rated tools to make this recipe successfully.
Instructions
- Step 1: Preheat oven to 375°F. Lightly grease a 9x13-inch baking dish with 1 tablespoon olive oil.
- Step 2: Cut 16 ounces refrigerated biscuit dough into quarters and scatter evenly in the bottom of the prepared dish.
- Step 3: Pour 1 1/2 cups pizza sauce evenly over the biscuit pieces, then sprinkle 1 cup pepperoni slices on top.
- Step 4: Layer 2 cups shredded mozzarella cheese evenly over the pepperoni and biscuit mixture.
- Step 5: Sprinkle 1 teaspoon dried Italian seasoning and 1/4 cup grated parmesan cheese over the top.
- Step 6: Bake uncovered for 25-30 minutes until biscuits are cooked through and golden at the edges, and cheese is bubbly and slightly browned.
- Step 7: Let cool for 5 minutes, then sprinkle 2 tablespoons chopped fresh basil over before slicing and serving.
Frequently asked questions
How long does Lazy Bubble Up Pizza Casserole take to make?
Total time is about 40 minutes (10 min prep + 30 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.
How do I store leftover Lazy Bubble Up Pizza Casserole?
Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep pepperoni slices from drying out.
Can I substitute ingredients in Lazy Bubble Up Pizza Casserole?
Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.
How do I scale Lazy Bubble Up Pizza Casserole for a different number of people?
The recipe is written for 6 servings. Multiply each ingredient by (your serving target / 6). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.
What goes well with Lazy Bubble Up Pizza Casserole?
Italian comfort food like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.
