Oven-Roasted Turkey Breast with Missouri Honey Mustard Glaze

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Tender oven-roasted turkey breast glazed with a sweet and tangy honey mustard sauce inspired by the heartland flavors of Missouri. This American-inspired pork recipe, ready in about 60 minutes, pairs boneless turkey breast, Missouri honey, Dijon mustard for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 280 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 50 min Serves 4 American cuisine 280 cal/serving
Build a week of meals around this recipe → Shop this recipe on Instacart → Shop equipment ↓

Ingredients

Affiliate disclosure: AislePrompt may earn a commission on qualifying purchases made through Amazon links, at no additional cost to you. See our policy →

Equipment for this recipe

Top-rated tools to make this recipe successfully.

More Kitchen tools → Shop all kitchen tools →

Instructions

  1. Step 1: Preheat the oven to 375°F. Pat dry 2 pounds of boneless turkey breast and place it on a roasting rack in a baking pan.
  2. Step 2: In a small bowl, whisk together 3 tablespoons Missouri honey, 2 tablespoons Dijon mustard, and 1 tablespoon olive oil until smooth.
  3. Step 3: Rub the turkey breast evenly with 1 teaspoon garlic powder, 1 teaspoon smoked paprika, 1 teaspoon salt, and 1/2 teaspoon black pepper.
  4. Step 4: Brush half of the honey mustard glaze over the turkey breast, reserving the rest for basting.
  5. Step 5: Roast the turkey breast for 45 minutes, basting with the remaining glaze every 15 minutes, until the internal temperature reaches 165°F and the glaze is caramelized.
  6. Step 6: Remove from oven and let rest for 10 minutes before slicing to serve.

Frequently asked questions

How long does Oven-Roasted Turkey Breast with Missouri Honey Mustard Glaze take to make?

Total time is about 60 minutes (10 min prep + 50 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Oven-Roasted Turkey Breast with Missouri Honey Mustard Glaze?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep boneless turkey breast from drying out.

Can I substitute ingredients in Oven-Roasted Turkey Breast with Missouri Honey Mustard Glaze?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Oven-Roasted Turkey Breast with Missouri Honey Mustard Glaze for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Oven-Roasted Turkey Breast with Missouri Honey Mustard Glaze?

American pork like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

Related recipes