Pan-Seared Catfish with Cajun-Spiced Corn and Tomato Relish

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

This dish features tender pan-seared catfish fillets paired with a vibrant Cajun-spiced corn and tomato relish that brings a balance of sweetness and heat. This southern-inspired seafood ready in about 25 minutes pairs about 6 oz each catfish fillets, Cajun seasoning, olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 320 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 15 min Serves 4 Southern cuisine 320 cal/serving
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Ingredients

Instructions

  1. Step 1: Pat dry 4 catfish fillets (6 oz each) and season both sides evenly with 2 tsp Cajun seasoning, 1/2 tsp salt, and 1/4 tsp black pepper.
  2. Step 2: Heat 2 tbsp olive oil in a large skillet over medium-high heat until shimmering. Add seasoned catfish fillets and sear for 4 minutes on each side until golden brown and cooked through with internal temperature of 145°F, then remove and keep warm.
  3. Step 3: In the same skillet, add 1 tbsp olive oil, 1 cup fresh corn kernels, 1 cup halved cherry tomatoes, 1/2 cup diced red bell pepper, and 1/4 cup diced red onion. Sauté for 5 minutes until the vegetables soften and the corn begins to caramelize.
  4. Step 4: Stir in 1 tbsp lemon juice and 2 tbsp chopped fresh parsley, then season with salt and black pepper to taste. Cook for another minute until fragrant.
  5. Step 5: Serve the catfish fillets topped with the warm Cajun-spiced corn and tomato relish.

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Frequently asked questions

How long does Pan-Seared Catfish with Cajun-Spiced Corn and Tomato Relish take to make?

Total time is about 25 minutes (10 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Pan-Seared Catfish with Cajun-Spiced Corn and Tomato Relish?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep cajun seasoning from drying out.

Can I substitute ingredients in Pan-Seared Catfish with Cajun-Spiced Corn and Tomato Relish?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Pan-Seared Catfish with Cajun-Spiced Corn and Tomato Relish for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Pan-Seared Catfish with Cajun-Spiced Corn and Tomato Relish?

Southern seafood like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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