Pan-Seared Pork Tenderloin with Honey-Mustard Glaze

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Juicy pork tenderloin medallions pan-seared to golden perfection and finished with a sweet and tangy honey-mustard sauce. This american-inspired pork (gluten free) ready in about 25 minutes pairs divided salt, divided black pepper, olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 280 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 15 min Serves 4 American cuisine 280 cal/serving
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Ingredients

Instructions

  1. Step 1: Season 1 lb pork tenderloin medallions evenly with 1/2 tsp salt and 1/4 tsp black pepper on both sides.
  2. Step 2: Heat 2 tbsp olive oil in a large skillet over medium-high heat until shimmering. Add pork medallions and sear for 3-4 minutes per side until golden brown and cooked through (internal temperature 145°F). Transfer to a plate and tent with foil.
  3. Step 3: Reduce heat to medium, add 2 minced garlic cloves to the skillet and sauté for 30 seconds until fragrant.
  4. Step 4: Stir in 3 tbsp Dijon mustard, 2 tbsp honey, 1 tbsp apple cider vinegar, remaining 1/2 tsp salt, and 1/4 tsp black pepper. Cook sauce for 2 minutes until slightly thickened.
  5. Step 5: Return pork medallions to the skillet, spoon the honey-mustard glaze over them, sprinkle 1 tsp chopped fresh thyme leaves, and cook for 1 minute more to heat through before serving.

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Frequently asked questions

How long does Pan-Seared Pork Tenderloin with Honey-Mustard Glaze take to make?

Total time is about 25 minutes (10 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Pan-Seared Pork Tenderloin with Honey-Mustard Glaze?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep divided salt from drying out.

Can I substitute ingredients in Pan-Seared Pork Tenderloin with Honey-Mustard Glaze?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Pan-Seared Pork Tenderloin with Honey-Mustard Glaze for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

Is Pan-Seared Pork Tenderloin with Honey-Mustard Glaze gluten free?

Yes — this recipe is tagged gluten free based on its ingredient list. Always cross-check labels for packaged ingredients (sauces, broths, condiments) since formulations vary by brand.

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