Sheet Pan Cajun-Spiced Blackened Catfish with Roasted Vegetables

By AislePrompt Editorial · Published 2026-05-19 · Updated 2026-05-19

A vibrant sheet pan dinner featuring tender catfish fillets coated in a smoky Cajun spice blend, roasted alongside colorful bell peppers and red onions for an effortless, flavorful meal. This Southern American-inspired seafood recipe, ready in about 28 minutes, pairs catfish fillets, olive oil, cajun seasoning for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 280 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Ingredients

• 4 fillets (6 oz each) catfish fillets
• 3 tbsp olive oil
• 2 tbsp cajun seasoning
• 1 large, sliced into 1/2-inch strips red bell pepper
• 1 large, sliced into 1/2-inch strips yellow bell pepper
• 1 medium, sliced into 1/4-inch wedges red onion
• 2 tbsp, freshly squeezed lemon juice
• 1 tsp garlic powder
• 1 tsp salt
• 1/2 tsp black pepper

The sheet pan we’d roast this on → Best Sheet Pans in 2026: Top Picks + Buying Guide

Instructions

1. Step 1: Preheat oven to 425°F. Line a large sheet pan with parchment paper. In a small bowl, combine 2 tbsp olive oil, 2 tbsp Cajun seasoning, 1 tsp garlic powder, 1 tsp salt, and 1/2 tsp black pepper to form a spice paste.
2. Step 2: Pat dry 4 catfish fillets with paper towels. Rub the Cajun spice paste evenly over both sides of each fillet. Place the fillets on one side of the prepared sheet pan.
3. Step 3: Toss 1 sliced red bell pepper, 1 sliced yellow bell pepper, and 1 sliced red onion with the remaining 1 tbsp olive oil and 2 tbsp lemon juice until well coated. Spread the vegetables evenly on the other side of the sheet pan.
4. Step 4: Roast in the preheated oven for 15-18 minutes until the catfish flakes easily with a fork and the vegetables are tender with slightly caramelized edges.
5. Step 5: Serve the blackened catfish fillets atop a bed of roasted vegetables, garnished with lemon wedges if desired.