Sheet Pan Cajun-Spiced Fish with Roasted Vegetables

By AislePrompt Editorial · Published 2026-05-05 · Updated 2026-05-05

Oven-roasted fish seasoned with bold Cajun spices paired with a medley of colorful roasted vegetables for a flavorful, easy dinner. This American-inspired sheet-pan recipe, ready in about 42 minutes, pairs olive oil, cajun seasoning, red bell pepper, sliced for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 280 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Ingredients

• 1 lb white fish fillets (such as cod or tilapia)
• 3 tbsp olive oil
• 2 tbsp cajun seasoning
• 1 large red bell pepper, sliced
• 1 medium zucchini, sliced into 1/2-inch rounds
• 1 medium yellow squash, sliced into 1/2-inch rounds
• 1 medium red onion, cut into wedges
• 1 tsp salt
• 1/2 tsp black pepper
• for serving fresh lemon wedges

The sheet pan we’d roast this on → Best Sheet Pans in 2026: Top Picks + Buying Guide

Instructions

1. Step 1: Preheat oven to 425°F (220°C). Line a large sheet pan with parchment paper.
2. Step 2: In a large bowl, toss 1 large sliced red bell pepper, 1 medium sliced zucchini, 1 medium sliced yellow squash, and 1 medium cut red onion with 2 tbsp olive oil, 1 tsp salt, and 1/2 tsp black pepper until evenly coated.
3. Step 3: Spread the vegetables evenly on the prepared sheet pan in a single layer and roast for 15 minutes.
4. Step 4: While vegetables roast, brush 1 lb white fish fillets with 1 tbsp olive oil and sprinkle 2 tbsp Cajun seasoning evenly over the fish.
5. Step 5: After 15 minutes, remove sheet pan from oven, stir vegetables, and nestle the seasoned fish fillets among the vegetables.
6. Step 6: Return the sheet pan to the oven and roast for an additional 10-12 minutes until the fish is opaque and flakes easily with a fork and the vegetables are tender.
7. Step 7: Serve immediately with fresh lemon wedges to squeeze over the fish.