Sheet Pan Honey-Mustard Glazed Salmon with Roasted Brussels Sprouts

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

An easy sheet pan dish featuring honey-mustard glazed salmon paired with caramelized Brussels sprouts, perfect for a quick yet elegant dinner. This american-inspired holiday ready in about 40 minutes pairs Dijon mustard, honey, divided olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 420 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart.

★ 4.5 (11 ratings) Prep: 10 min Cook: 30 min Serves 4 American cuisine 420 cal/serving
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Ingredients

Instructions

  1. Step 1: Preheat oven to 400°F. On a large rimmed baking sheet, toss 1 pound halved Brussels sprouts with 2 tablespoons olive oil, 1/2 teaspoon garlic powder, 1/2 teaspoon kosher salt, and 1/4 teaspoon black pepper. Spread in an even layer and roast for 15 minutes.
  2. Step 2: Meanwhile, in a small bowl, whisk together 3 tablespoons Dijon mustard and 2 tablespoons honey until smooth.
  3. Step 3: Remove the baking sheet from oven and push Brussels sprouts to one side. Place 4 salmon fillets skin-side down on the empty side and brush each fillet generously with the honey-mustard glaze.
  4. Step 4: Drizzle the remaining 1 tablespoon olive oil and season the salmon with 1/2 teaspoon kosher salt and 1/4 teaspoon black pepper.
  5. Step 5: Return the pan to the oven and roast for 12-15 minutes, until the salmon flakes easily with a fork and Brussels sprouts are caramelized.
  6. Step 6: Serve immediately with lemon wedges for squeezing over the salmon and vegetables.

Frequently asked questions

How long does Sheet Pan Honey-Mustard Glazed Salmon with Roasted Brussels Sprouts take to make?

Total time is about 40 minutes (10 min prep + 30 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Sheet Pan Honey-Mustard Glazed Salmon with Roasted Brussels Sprouts?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep dijon mustard from drying out.

Can I substitute ingredients in Sheet Pan Honey-Mustard Glazed Salmon with Roasted Brussels Sprouts?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Sheet Pan Honey-Mustard Glazed Salmon with Roasted Brussels Sprouts for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Sheet Pan Honey-Mustard Glazed Salmon with Roasted Brussels Sprouts?

American holiday like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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