Sheet Pan Regional Spiced Pork Tenderloin with Roasted Vegetables

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

A simple sheet pan dinner featuring pork tenderloin rubbed with regional spices, roasted alongside sweet potatoes and green beans for a balanced meal. This american-inspired pork ready in about 55 minutes pairs pork tenderloin, trimmed green beans, olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 400 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 40 min Serves 4 American cuisine 400 cal/serving
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Ingredients

Instructions

  1. Step 1: Preheat oven to 425°F. In a small bowl, combine 2 tsp regional spice blend (equal parts paprika, cumin, garlic powder), 1.5 tsp salt, and 1 tsp black pepper.
  2. Step 2: Rub 1.5 lbs pork tenderloin all over with 2 tbsp olive oil and then the spice mixture evenly. Place tenderloin in center of large rimmed baking sheet.
  3. Step 3: Toss 2 medium peeled and cubed sweet potatoes with 2 tbsp olive oil and a pinch of salt and pepper. Spread sweet potatoes on one side of the pan.
  4. Step 4: Toss 12 oz trimmed green beans with a drizzle of olive oil and small pinch of salt and pepper. Spread green beans on the other side of the pan.
  5. Step 5: Roast everything for 25 minutes, then flip sweet potatoes and green beans for even roasting. Continue roasting for another 10-15 minutes until pork reaches 145°F internal temperature and vegetables are tender and slightly caramelized.
  6. Step 6: Remove pork from oven and let rest for 5 minutes before slicing. Serve slices with roasted sweet potatoes and green beans.

Equipment for this recipe

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Frequently asked questions

How long does Sheet Pan Regional Spiced Pork Tenderloin with Roasted Vegetables take to make?

Total time is about 55 minutes (15 min prep + 40 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Sheet Pan Regional Spiced Pork Tenderloin with Roasted Vegetables?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep pork tenderloin from drying out.

Can I substitute ingredients in Sheet Pan Regional Spiced Pork Tenderloin with Roasted Vegetables?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Sheet Pan Regional Spiced Pork Tenderloin with Roasted Vegetables for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Sheet Pan Regional Spiced Pork Tenderloin with Roasted Vegetables?

American pork like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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