Sioux Falls-Inspired Beef and Cheddar Sandwich with Horseradish Aioli

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

A savory sandwich featuring tender roast beef from Sioux Falls paired with sharp cheddar and a zesty horseradish aioli on toasted sourdough. This american-inspired sandwiches & wraps ready in about 20 minutes blends roast beef slices, sharp cheddar cheese slices, sourdough bread slices into a versatile sauce that lifts everything from grain bowls and roasted vegetables to grilled proteins — a small-batch staple worth keeping in the fridge. Each serving lands at about 650 calories and feeds 1, so a small batch covers several meals across the week without taking over the fridge. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 10 min Serves 1 American cuisine 650 cal/serving
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Ingredients

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Instructions

  1. Step 1: In a small bowl, mix 2 tbsp mayonnaise with 1 tsp prepared horseradish and 1 tsp Dijon mustard until smooth. Set aside.
  2. Step 2: Heat a skillet over medium heat. Butter 1 tbsp on one side of each of the 2 sourdough bread slices.
  3. Step 3: Place one bread slice butter-side-down in the skillet. Layer 6 oz roast beef slices, 2 sharp cheddar cheese slices, and 1/4 cup arugula leaves on the bread.
  4. Step 4: Spread the horseradish aioli evenly on the other bread slice, then place it aioli-side-down on top of the sandwich.
  5. Step 5: Grill the sandwich for 3-4 minutes per side until bread is golden brown and cheese is melted. Sprinkle 1/4 tsp black pepper over arugula before closing the sandwich.
  6. Step 6: Remove from heat, slice in half, and serve warm.

Frequently asked questions

How long does Sioux Falls-Inspired Beef and Cheddar Sandwich with Horseradish Aioli take to make?

Total time is about 20 minutes (10 min prep + 10 min cook). A small batch typically covers several meals in the week — store as the recipe directs.

How do I store leftover Sioux Falls-Inspired Beef and Cheddar Sandwich with Horseradish Aioli?

Transfer to an airtight jar and refrigerate for up to 5–7 days. Most sauces freeze well for up to 2 months — portion into small containers or freezer bags so you can thaw only what you need. Stir before serving; cream- or yogurt-based sauces may separate on standing.

Can I substitute ingredients in Sioux Falls-Inspired Beef and Cheddar Sandwich with Horseradish Aioli?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Sioux Falls-Inspired Beef and Cheddar Sandwich with Horseradish Aioli for a different number of people?

The recipe is written for 1 servings. Multiply each ingredient by (your serving target / 1). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Sioux Falls-Inspired Beef and Cheddar Sandwich with Horseradish Aioli?

American sandwiches & wraps like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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