Slow-Cooked Southern Illinois Pulled Pork with Tangy Vinegar Sauce

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Tender pulled pork slow-cooked with classic Southern Illinois flavors, served with a tangy vinegar-based sauce that balances smoky and spicy notes. This American-inspired pork recipe, ready in about 255 minutes, pairs pork shoulder, apple cider vinegar, yellow mustard for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 450 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 240 min Serves 6 American cuisine 450 cal/serving
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Ingredients

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Instructions

  1. Step 1: Preheat oven to 300°F. Mix 1 tbsp salt, 1 tsp black pepper, 1 tbsp smoked paprika, 1 tsp garlic powder, and 1 tsp onion powder in a bowl. Rub this dry spice mix evenly over 3 lbs pork shoulder.
  2. Step 2: Heat 2 tbsp olive oil in a large oven-safe pot over medium-high heat. Sear the pork shoulder on all sides, about 3-4 minutes per side until browned and crispy edges form.
  3. Step 3: In a separate bowl, combine 1/2 cup apple cider vinegar, 2 tbsp yellow mustard, 2 tbsp brown sugar, 1/2 tsp red pepper flakes, and 1 cup water. Pour this vinegar sauce around the pork in the pot.
  4. Step 4: Cover the pot tightly with a lid or foil and place in the preheated oven. Slow cook for 4 hours, basting the pork every hour with the vinegar sauce to keep it moist.
  5. Step 5: Remove pork from oven and shred using two forks; mix shredded meat with the pan juices and vinegar sauce. Serve warm with coleslaw or cornbread.

Frequently asked questions

How long does Slow-Cooked Southern Illinois Pulled Pork with Tangy Vinegar Sauce take to make?

Total time is about 255 minutes (15 min prep + 240 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Slow-Cooked Southern Illinois Pulled Pork with Tangy Vinegar Sauce?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep pork shoulder from drying out.

Can I substitute ingredients in Slow-Cooked Southern Illinois Pulled Pork with Tangy Vinegar Sauce?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Slow-Cooked Southern Illinois Pulled Pork with Tangy Vinegar Sauce for a different number of people?

The recipe is written for 6 servings. Multiply each ingredient by (your serving target / 6). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Slow-Cooked Southern Illinois Pulled Pork with Tangy Vinegar Sauce?

American pork like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.