Slow Cooker Bourbon-Glazed Beef Brisket with Lexington Spices

By AislePrompt Editorial · Published 2026-07-01 · Updated 2026-07-01

Tender slow-cooked beef brisket infused with a rich bourbon glaze and warm Lexington-inspired spices, perfect for a comforting dinner. This American-inspired beef recipe, ready in about 495 minutes, pairs beef brisket, salt, black pepper for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 450 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Ingredients

• 3 lbs beef brisket
• 2 tsp salt
• 1 tsp black pepper
• 1 tsp smoked paprika
• 1 tsp garlic powder
• 1 tsp onion powder
• 2 tbsp olive oil
• 1/2 cup bourbon whiskey
• 1/4 cup brown sugar
• 2 tbsp apple cider vinegar
• 2 tbsp Worcestershire sauce
• 1 cup beef broth
• 1 tbsp yellow mustard

The slow cooker we’d leave this in all day → Best Slow Cookers in 2026: Top Picks + Buying Guide

Instructions

1. Step 1: Combine 2 tsp salt, 1 tsp black pepper, 1 tsp smoked paprika, 1 tsp garlic powder, and 1 tsp onion powder in a small bowl; rub evenly over all sides of 3 lbs beef brisket.
2. Step 2: Heat 2 tbsp olive oil in a large skillet over medium-high heat and sear brisket on all sides until browned, about 3 minutes per side.
3. Step 3: In a bowl, whisk together 1/2 cup bourbon whiskey, 1/4 cup brown sugar, 2 tbsp apple cider vinegar, 2 tbsp Worcestershire sauce, 1 cup beef broth, and 1 tbsp yellow mustard until sugar dissolves.
4. Step 4: Place seared brisket in slow cooker and pour bourbon glaze mixture over it; cover and cook on low for 8 hours until brisket is fork-tender.
5. Step 5: Remove brisket and tent with foil; pour cooking liquid into a saucepan and simmer over medium heat for 10 minutes until sauce thickens slightly, then slice brisket against the grain and serve with the bourbon glaze.