Spiced Cajun Po'Boy Sandwich with Remoulade Sauce

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

A classic New Orleans po'boy sandwich filled with crispy spiced fried shrimp and tangy remoulade sauce on a crusty French roll. This creole-inspired sandwiches & wraps ready in about 35 minutes blends Medium shrimp, peeled and deveined, Cajun seasoning, All-purpose flour into a versatile sauce that lifts everything from grain bowls and roasted vegetables to grilled proteins — a small-batch staple worth keeping in the fridge. Each serving lands at about 550 calories and feeds 4, so a small batch covers several meals across the week without taking over the fridge. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 20 min Cook: 15 min Serves 4 Creole cuisine 550 cal/serving
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Ingredients

Instructions

  1. Step 1: In a large bowl, toss 1 lb medium peeled shrimp with 2 tbsp Cajun seasoning until evenly coated.
  2. Step 2: Pour 1 cup buttermilk into a separate bowl. Place 1 cup all-purpose flour in another shallow dish.
  3. Step 3: Dip each shrimp first into the buttermilk, then dredge in flour, shaking off excess.
  4. Step 4: Heat 4 cups vegetable oil in a deep skillet or fryer to 350°F. Fry shrimp in batches for 2-3 minutes until golden brown and crispy. Drain on paper towels.
  5. Step 5: To make remoulade sauce, whisk together 1/2 cup mayonnaise, 1 tbsp Dijon mustard, 1 tsp horseradish, 1 tsp Worcestershire sauce, 1 tsp hot sauce, 1 tbsp lemon juice, 1 tbsp chopped parsley, 1 tsp salt, and 1/2 tsp black pepper until smooth.
  6. Step 6: Slice 4 French bread rolls lengthwise without cutting all the way through. Spread remoulade sauce generously inside each roll.
  7. Step 7: Layer with 1 cup shredded lettuce, 1 cup sliced tomatoes, and the fried shrimp. Serve immediately.

Equipment for this recipe

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Frequently asked questions

How long does Spiced Cajun Po'Boy Sandwich with Remoulade Sauce take to make?

Total time is about 35 minutes (20 min prep + 15 min cook). A small batch typically covers several meals in the week — store as the recipe directs.

How do I store leftover Spiced Cajun Po'Boy Sandwich with Remoulade Sauce?

Transfer to an airtight jar and refrigerate for up to 5–7 days. Most sauces freeze well for up to 2 months — portion into small containers or freezer bags so you can thaw only what you need. Stir before serving; cream- or yogurt-based sauces may separate on standing.

Can I substitute ingredients in Spiced Cajun Po'Boy Sandwich with Remoulade Sauce?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Spiced Cajun Po'Boy Sandwich with Remoulade Sauce for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Spiced Cajun Po'Boy Sandwich with Remoulade Sauce?

Creole sandwiches & wraps like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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