Spicy New Orleans-Inspired Shrimp Po’Boy Sandwich

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

A vibrant sandwich featuring crispy fried shrimp, spicy remoulade, and crisp lettuce on a soft French roll, inspired by Hyde Park’s celebrated po’boys. This american-inspired sandwiches & wraps ready in about 40 minutes pairs large shrimp, peeled and deveined, buttermilk, all-purpose flour for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 600 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 25 min Cook: 15 min Serves 4 American cuisine 600 cal/serving
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Ingredients

Instructions

  1. Step 1: In a medium bowl, soak 1 lb peeled and deveined large shrimp in 1 cup buttermilk for 20 minutes in the refrigerator.
  2. Step 2: In a shallow dish, combine 1 cup all-purpose flour, 1/2 cup cornmeal, 2 tsp Cajun seasoning, and 1/2 tsp salt.
  3. Step 3: Heat 2 cups vegetable oil in a deep skillet over medium-high heat to 350°F.
  4. Step 4: Remove shrimp from buttermilk, letting excess drip off, then dredge in the flour mixture, coating completely.
  5. Step 5: Fry shrimp in batches for 2-3 minutes each until golden brown and cooked through, then drain on paper towels.
  6. Step 6: In a small bowl, whisk together 1/2 cup mayonnaise, 2 tbsp Dijon mustard, 1 tbsp hot sauce, 1 tbsp lemon juice, 1 tsp salt, and 1/2 tsp garlic powder until smooth to make the remoulade sauce.
  7. Step 7: Slice 4 French rolls lengthwise without cutting all the way through, and toast lightly.
  8. Step 8: Spread a generous 2 tbsp of remoulade sauce inside each roll, then layer with 1/2 cup shredded iceberg lettuce, 1/4 cup sliced tomatoes, and a pile of the fried shrimp.
  9. Step 9: Close sandwiches and serve immediately for best texture and flavor.

Equipment for this recipe

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Frequently asked questions

How long does Spicy New Orleans-Inspired Shrimp Po’Boy Sandwich take to make?

Total time is about 40 minutes (25 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Spicy New Orleans-Inspired Shrimp Po’Boy Sandwich?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep buttermilk from drying out.

Can I substitute ingredients in Spicy New Orleans-Inspired Shrimp Po’Boy Sandwich?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Spicy New Orleans-Inspired Shrimp Po’Boy Sandwich for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Spicy New Orleans-Inspired Shrimp Po’Boy Sandwich?

American sandwiches & wraps like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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