Spicy Po’Boy Sandwich with Fried Catfish and Remoulade

By AislePrompt Editorial · Published 2026-05-23 · Updated 2026-05-23

A classic New Orleans sandwich featuring crispy fried catfish, crisp lettuce, tomato slices, and a zesty remoulade sauce on a French roll. This Louisiana Creole-inspired sandwich and wrap recipe, ready in about 45 minutes, pairs catfish fillets, buttermilk, all-purpose flour for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 550 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Ingredients

• 1 lb catfish fillets
• 1 cup buttermilk
• 1 cup all-purpose flour
• 1/2 cup cornmeal
• 1 tbsp Cajun seasoning
• 2 cups vegetable oil
• 4 French rolls
• 1 cup shredded iceberg lettuce
• 1 cup sliced tomatoes
• 1/2 cup mayonnaise
• 1 tbsp Dijon mustard
• 1 tsp prepared horseradish
• 1 tbsp hot sauce
• 1 tsp paprika
• 1 tbsp lemon juice
• 1 tsp minced garlic

The pan we’d use for this → Best Nonstick Cookware for 2026: Top 5 Skillet Picks + Buying Guide

Instructions

1. Step 1: In a shallow dish, combine 1 cup buttermilk with 1 tbsp Cajun seasoning. Submerge 1 lb catfish fillets and marinate for 20 minutes.
2. Step 2: In another bowl, mix 1 cup all-purpose flour, 1/2 cup cornmeal, and 1 tsp paprika.
3. Step 3: Heat 2 cups vegetable oil in a deep skillet over medium-high heat until it reaches 350°F.
4. Step 4: Remove catfish from buttermilk, dredge in flour-cornmeal mixture, shaking off excess.
5. Step 5: Fry catfish in hot oil for 3-4 minutes per side until golden brown and crispy. Drain on paper towels.
6. Step 6: For remoulade sauce, whisk together 1/2 cup mayonnaise, 1 tbsp Dijon mustard, 1 tsp prepared horseradish, 1 tbsp hot sauce, 1 tbsp lemon juice, and 1 tsp minced garlic until smooth.
7. Step 7: Slice 4 French rolls lengthwise, spread remoulade sauce generously inside each roll.
8. Step 8: Layer each roll with fried catfish, 1 cup shredded iceberg lettuce, and 1 cup sliced tomatoes.
9. Step 9: Serve immediately while hot and crisp.