Spicy Po’Boy Sandwich with Fried Catfish and Remoulade
A classic New Orleans sandwich featuring crispy fried catfish, crisp lettuce, tomato slices, and a zesty remoulade sauce on a French roll. This Louisiana Creole-inspired sandwich and wrap recipe, ready in about 45 minutes, pairs catfish fillets, buttermilk, all-purpose flour for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 550 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.
Ingredients
- 1 lb catfish fillets
- 1 cup buttermilk
- 1 cup all-purpose flour
- 1/2 cup cornmeal
- 1 tbsp Cajun seasoning
- 2 cups vegetable oil
- 4 French rolls
- 1 cup shredded iceberg lettuce
- 1 cup sliced tomatoes
- 1/2 cup mayonnaise
- 1 tbsp Dijon mustard
- 1 tsp prepared horseradish
- 1 tbsp hot sauce
- 1 tsp paprika
- 1 tbsp lemon juice
- 1 tsp minced garlic
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Equipment for this recipe
Top-rated tools to make this recipe successfully.
Instructions
- Step 1: In a shallow dish, combine 1 cup buttermilk with 1 tbsp Cajun seasoning. Submerge 1 lb catfish fillets and marinate for 20 minutes.
- Step 2: In another bowl, mix 1 cup all-purpose flour, 1/2 cup cornmeal, and 1 tsp paprika.
- Step 3: Heat 2 cups vegetable oil in a deep skillet over medium-high heat until it reaches 350°F.
- Step 4: Remove catfish from buttermilk, dredge in flour-cornmeal mixture, shaking off excess.
- Step 5: Fry catfish in hot oil for 3-4 minutes per side until golden brown and crispy. Drain on paper towels.
- Step 6: For remoulade sauce, whisk together 1/2 cup mayonnaise, 1 tbsp Dijon mustard, 1 tsp prepared horseradish, 1 tbsp hot sauce, 1 tbsp lemon juice, and 1 tsp minced garlic until smooth.
- Step 7: Slice 4 French rolls lengthwise, spread remoulade sauce generously inside each roll.
- Step 8: Layer each roll with fried catfish, 1 cup shredded iceberg lettuce, and 1 cup sliced tomatoes.
- Step 9: Serve immediately while hot and crisp.
Frequently asked questions
How long does Spicy Po’Boy Sandwich with Fried Catfish and Remoulade take to make?
Total time is about 45 minutes (30 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.
How do I store leftover Spicy Po’Boy Sandwich with Fried Catfish and Remoulade?
Refrigerate in a covered airtight container for up to 3–4 days (FDA FoodKeeper guideline for cooked fish). Store any fresh salsa or citrus-based garnish in a separate container — it keeps for up to 2 days. Freeze cooked fish (without fresh garnishes) for up to 3 months; thaw overnight in the fridge and reheat gently at 275°F until just warmed through to preserve texture.
Can I substitute ingredients in Spicy Po’Boy Sandwich with Fried Catfish and Remoulade?
Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.
How do I scale Spicy Po’Boy Sandwich with Fried Catfish and Remoulade for a different number of people?
The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.
What goes well with Spicy Po’Boy Sandwich with Fried Catfish and Remoulade?
Louisiana Creole sandwiches & wraps like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.
