Spiced Cajun Po’Boy Sandwich with Remoulade Sauce

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

A classic New Orleans po’boy sandwich loaded with crispy fried shrimp, dressed with zesty remoulade and crisp lettuce on a French roll. This Creole-inspired sandwich and wrap recipe, ready in about 35 minutes, pairs medium shrimp, peeled and deveined, all-purpose flour, cornmeal for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 550 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 20 min Cook: 15 min Serves 4 Creole cuisine 550 cal/serving
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Ingredients

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Instructions

  1. Step 1: In a large bowl, whisk together 1 cup all-purpose flour, 1/2 cup cornmeal, and 2 tbsp Cajun seasoning. Pour 1 cup buttermilk into another bowl.
  2. Step 2: Dip 1 lb peeled and deveined shrimp first in the buttermilk, then dredge thoroughly in the seasoned flour mixture, shaking off excess.
  3. Step 3: Heat 4 cups vegetable oil in a deep skillet or fryer to 350°F. Fry the shrimp in batches for 2-3 minutes until golden brown and crispy. Drain on paper towels.
  4. Step 4: To prepare remoulade sauce, whisk together 1/2 cup mayonnaise, 1 tbsp Dijon mustard, 1 tbsp lemon juice, 1 tsp Worcestershire sauce, 1 tsp hot sauce, 1 minced garlic clove, 1 tsp paprika, 1/2 tsp salt, and 1/4 tsp black pepper until smooth.
  5. Step 5: Slice 4 French bread rolls lengthwise without cutting completely through. Spread a generous layer of remoulade sauce inside each roll.
  6. Step 6: Layer 1 cup shredded iceberg lettuce and slices from 1 large tomato evenly in the rolls. Top with the hot fried shrimp.
  7. Step 7: Close the sandwiches and serve immediately for a satisfying crunchy and spicy po’boy experience.

Frequently asked questions

How long does Spiced Cajun Po’Boy Sandwich with Remoulade Sauce take to make?

Total time is about 35 minutes (20 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Spiced Cajun Po’Boy Sandwich with Remoulade Sauce?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep all-purpose flour from drying out.

Can I substitute ingredients in Spiced Cajun Po’Boy Sandwich with Remoulade Sauce?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Spiced Cajun Po’Boy Sandwich with Remoulade Sauce for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Spiced Cajun Po’Boy Sandwich with Remoulade Sauce?

Creole sandwiches & wraps like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.