X-Ray Crystallography Inspired Penicillin Herb Roasted Chicken
Roasted chicken infused with a medley of fresh herbs and garlic, inspired by Dorothy Hodgkin’s groundbreaking work on penicillin structure. This French recipe, ready in about 90 minutes, pairs whole chicken, fresh rosemary, fresh thyme for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 450 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.
Ingredients
- 4 lbs whole chicken
- 2 tbsp, chopped fresh rosemary
- 2 tbsp, chopped fresh thyme
- 6, minced garlic cloves
- 3 tbsp olive oil
- 1, halved lemon
- 2 tsp salt
- 1 tsp black pepper
- 2 tbsp, softened butter
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Equipment for this recipe
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Instructions
- Step 1: Preheat oven to 425°F (220°C). In a small bowl, mix 3 tbsp olive oil, 6 minced garlic cloves, 2 tbsp chopped rosemary, 2 tbsp chopped thyme, 2 tsp salt, and 1 tsp black pepper to create a herb paste.
- Step 2: Pat dry a 4 lb whole chicken with paper towels. Gently loosen the skin over the breasts and thighs and rub half of the herb paste under the skin. Rub the remaining paste all over the outside of the chicken.
- Step 3: Stuff the chicken cavity with 1 halved lemon and place it breast side up on a roasting rack inside a roasting pan. Spread 2 tbsp softened butter over the skin.
- Step 4: Roast the chicken for 20 minutes at 425°F, then reduce heat to 375°F (190°C) and continue roasting for 45-55 minutes, or until the internal temperature reaches 165°F (74°C) and the skin is golden brown and crisp. Let rest for 10 minutes before carving.








