Baked Cajun-Spiced Salmon with Garlic Butter
Salmon fillets baked with a smoky Cajun spice rub and topped with melted garlic butter for a succulent, flavorful main dish. This American-inspired seafood recipe, ready in about 20 minutes, pairs salmon fillets, Cajun seasoning, unsalted butter for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 360 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.
Ingredients
- 4 pieces (6 oz each) salmon fillets
- 2 tbsp Cajun seasoning
- 4 tbsp unsalted butter
- 3 minced garlic cloves
- 4 lemon wedges
- 2 tbsp chopped fresh parsley
- 1 tsp salt
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Equipment for this recipe
Tools this recipe's steps call for, with a link to each on Amazon.
Instructions
- Step 1: Preheat oven to 400°F. Place 4 salmon fillets skin-side down on a lined baking sheet and season evenly with 2 tbsp Cajun seasoning and 1 tsp salt.
- Step 2: In a small saucepan over medium heat, melt 4 tbsp unsalted butter with 3 minced garlic cloves, stirring for 2 minutes until fragrant and the garlic softens.
- Step 3: Spoon the garlic butter evenly over the salmon fillets and bake in the oven for 12-15 minutes until the salmon flakes easily with a fork.
- Step 4: Remove from oven, sprinkle 2 tbsp chopped fresh parsley over the fillets, and serve immediately with 4 lemon wedges for squeezing.








