Charred Mezcal-Lime Shrimp Skewers with Oaxacan Spice Rub

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Juicy shrimp marinated in mezcal, lime, and Oaxacan spices, then grilled to smoky perfection on skewers. This Mexican-inspired seafood recipe, ready in about 45 minutes, pairs large shrimp, mezcal, fresh lime juice for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 220 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 35 min Cook: 10 min Serves 4 Mexican cuisine 220 cal/serving
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Ingredients

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Instructions

  1. Step 1: In a medium bowl, combine 3 tbsp mezcal, 2 tbsp fresh lime juice, 2 minced garlic cloves, 1 tsp chili powder, 1 tsp dried oregano, 1/2 tsp ground cumin, 1 tsp smoked paprika, 1 tsp salt, 1/2 tsp black pepper, and 1 tbsp vegetable oil to form the marinade.
  2. Step 2: Add 1 lb peeled and deveined large shrimp to the marinade and toss to coat thoroughly. Cover and refrigerate for 30 minutes to absorb flavors.
  3. Step 3: Preheat grill or grill pan to medium-high heat (around 400°F). Thread shrimp onto 6 soaked wooden skewers, about 5-6 shrimp per skewer.
  4. Step 4: Grill shrimp skewers for 2-3 minutes per side until pink and opaque with slight char marks, basting occasionally with leftover marinade.
  5. Step 5: Remove from grill and serve immediately with lime wedges and fresh cilantro if desired.

Frequently asked questions

How long does Charred Mezcal-Lime Shrimp Skewers with Oaxacan Spice Rub take to make?

Total time is about 45 minutes (35 min prep + 10 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Charred Mezcal-Lime Shrimp Skewers with Oaxacan Spice Rub?

Refrigerate in a covered airtight container for up to 3–4 days (FDA FoodKeeper guideline for cooked fish). Store any fresh salsa or citrus-based garnish in a separate container — it keeps for up to 2 days. Freeze cooked fish (without fresh garnishes) for up to 3 months; thaw overnight in the fridge and reheat gently at 275°F until just warmed through to preserve texture.

Can I substitute ingredients in Charred Mezcal-Lime Shrimp Skewers with Oaxacan Spice Rub?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Charred Mezcal-Lime Shrimp Skewers with Oaxacan Spice Rub for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Charred Mezcal-Lime Shrimp Skewers with Oaxacan Spice Rub?

Mexican seafood like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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