Cranberry-Orange Glazed Ham with Roasted Brussels Sprouts

By Lauren Mitchell, Test Kitchen Director · Reviewed by AislePrompt Editorial · Published 2026-05-05 · Updated 2026-05-05

A savory ham glazed with a tangy cranberry-orange sauce, paired with oven-roasted Brussels sprouts for a balanced holiday entrée. This American-inspired holiday recipe, ready in about 115 minutes, pairs bone-in ham, fully cooked, fresh cranberries, orange juice, freshly squeezed for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 400 calories and feeds 8, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Ingredients

• 5 pounds bone-in ham, fully cooked
• 1 1/2 cups fresh cranberries
• 1/2 cup orange juice, freshly squeezed
• 1/3 cup brown sugar
• 2 tablespoons Dijon mustard
• 4 cups Brussels sprouts, halved
• 3 tablespoons olive oil
• 1 teaspoon salt
• 1/2 teaspoon black pepper
• 1/4 teaspoon ground cinnamon

Instructions

1. Step 1: Preheat oven to 325°F. Score the surface of the 5-pound bone-in fully cooked ham in a diamond pattern about 1/4-inch deep.
2. Step 2: In a small saucepan over medium heat, combine 1 1/2 cups fresh cranberries, 1/2 cup freshly squeezed orange juice, 1/3 cup brown sugar, 2 tablespoons Dijon mustard, and 1/4 teaspoon ground cinnamon. Cook, stirring occasionally, for 10 minutes until cranberries burst and sauce thickens.
3. Step 3: Place the ham on a large roasting pan and brush half the cranberry-orange glaze evenly over the surface.
4. Step 4: Roast the ham for 1 hour 15 minutes, basting every 20 minutes with remaining glaze, until heated through and caramelized.
5. Step 5: Meanwhile, toss 4 cups halved Brussels sprouts with 3 tablespoons olive oil, 1 teaspoon salt, and 1/2 teaspoon black pepper in a bowl.
6. Step 6: Spread Brussels sprouts on a baking sheet and roast in the oven alongside the ham for 25-30 minutes until tender and browned on edges.
7. Step 7: Remove ham and Brussels sprouts from oven. Let ham rest 10 minutes before slicing. Serve ham slices topped with any pan glaze alongside the roasted Brussels sprouts.