Creole-Style Po’Boy Sandwich with Fried Catfish and Remoulade

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

A classic New Orleans po’boy loaded with crispy fried catfish, crisp lettuce, juicy tomatoes, and tangy remoulade sauce on crusty French bread. This louisiana creole-inspired sandwiches & wraps ready in about 35 minutes pairs cut into 4 pieces catfish fillets, buttermilk, cornmeal for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 520 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 20 min Cook: 15 min Serves 4 Louisiana Creole cuisine 520 cal/serving
Plan a meal with the AI → Shop this recipe on Instacart → Shop equipment ↓

Ingredients

Instructions

  1. Step 1: Pour 1 cup buttermilk into a shallow dish. In another shallow dish, combine 1 cup cornmeal, 1/2 cup all-purpose flour, 1 tbsp Cajun seasoning, salt, and black pepper to taste.
  2. Step 2: Dip each of the 4 catfish fillet pieces into the buttermilk, then dredge in the cornmeal mixture, pressing gently to coat evenly.
  3. Step 3: Heat about 3 cups vegetable oil in a deep skillet over medium-high heat to 350°F. Fry catfish pieces in batches for 3-4 minutes per side until golden brown and crispy. Drain on paper towels.
  4. Step 4: To make remoulade sauce, whisk together 1/2 cup mayonnaise, 2 tbsp Dijon mustard, 1 tbsp prepared horseradish, 1 tsp Worcestershire sauce, 1 tsp hot sauce, 1 tbsp lemon juice, and 1 tsp minced garlic until smooth.
  5. Step 5: Lightly toast 4 French baguette rolls, then spread about 2 tbsp remoulade sauce on the bottom halves. Layer each with 1 leaf leaf lettuce, 2-3 slices ripe tomato, and the fried catfish fillet.
  6. Step 6: Top with the other half of the roll and serve immediately with extra remoulade on the side.

Equipment for this recipe

Top-rated tools to make this recipe successfully.

More Knives & cutting boards → Shop all kitchen tools →

Frequently asked questions

How long does Creole-Style Po’Boy Sandwich with Fried Catfish and Remoulade take to make?

Total time is about 35 minutes (20 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Creole-Style Po’Boy Sandwich with Fried Catfish and Remoulade?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep buttermilk from drying out.

Can I substitute ingredients in Creole-Style Po’Boy Sandwich with Fried Catfish and Remoulade?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Creole-Style Po’Boy Sandwich with Fried Catfish and Remoulade for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Creole-Style Po’Boy Sandwich with Fried Catfish and Remoulade?

Louisiana Creole sandwiches & wraps like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.