Grilled Cajun-Spiced Chicken with Smoky Texas BBQ Sauce

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Juicy grilled chicken breasts seasoned with a bold Cajun spice rub paired with a smoky homemade Texas-style BBQ sauce for a flavorful Southern meal. This bbq & smoked-inspired chicken ready in about 35 minutes blends (6 oz each) chicken breasts, olive oil, paprika into a versatile sauce that lifts everything from grain bowls and roasted vegetables to grilled proteins — a small-batch staple worth keeping in the fridge. Each serving lands at about 320 calories and feeds 4, so a small batch covers several meals across the week without taking over the fridge. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 20 min Serves 4 320 cal/serving
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Ingredients

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Instructions

  1. Step 1: Preheat your grill to medium-high heat (about 400°F). In a small bowl, mix 2 tsp paprika, 1 tsp cayenne pepper, 1 tsp garlic powder, 1 tsp onion powder, 1/2 tsp dried oregano, 1 tsp salt, and 1/2 tsp black pepper to create the Cajun spice rub.
  2. Step 2: Rub 4 chicken breasts evenly with 2 tbsp olive oil, then coat them thoroughly with the Cajun spice mix. Set aside to rest for 10 minutes.
  3. Step 3: While the chicken rests, combine 1 cup ketchup, 2 tbsp apple cider vinegar, 2 tbsp brown sugar, 1 tsp smoked paprika, 1 tbsp Worcestershire sauce, 1/2 tsp mustard powder, and 1/2 tsp chipotle chili powder in a saucepan over medium heat. Simmer gently for 10 minutes until the sauce thickens and the flavors meld.
  4. Step 4: Place the seasoned chicken breasts on the preheated grill and cook for 6-7 minutes per side, turning once, until internal temperature reaches 165°F and the exterior has nice grill marks.
  5. Step 5: Brush the chicken with the smoky BBQ sauce during the last 2 minutes of grilling on each side to caramelize the glaze. Remove from the grill and let rest for 5 minutes before serving with extra BBQ sauce on the side.

Frequently asked questions

How long does Grilled Cajun-Spiced Chicken with Smoky Texas BBQ Sauce take to make?

Total time is about 35 minutes (15 min prep + 20 min cook). A small batch typically covers several meals in the week — store as the recipe directs.

How do I store leftover Grilled Cajun-Spiced Chicken with Smoky Texas BBQ Sauce?

Transfer to an airtight jar and refrigerate for up to 5–7 days. Most sauces freeze well for up to 2 months — portion into small containers or freezer bags so you can thaw only what you need. Stir before serving; cream- or yogurt-based sauces may separate on standing.

Can I substitute ingredients in Grilled Cajun-Spiced Chicken with Smoky Texas BBQ Sauce?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Grilled Cajun-Spiced Chicken with Smoky Texas BBQ Sauce for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Grilled Cajun-Spiced Chicken with Smoky Texas BBQ Sauce?

BBQ & Smoked chicken like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.