Lazy Bubble Up Pizza Casserole
A fun, layered casserole that bubbles up cheesy tomato sauce and pepperoni over soft biscuit dough for an effortless pizza night. This Italian-inspired comfort-food recipe, ready in about 40 minutes, pairs refrigerated biscuit dough, pepperoni slices, mozzarella cheese for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 620 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.
Ingredients
- 16 oz (1 tube) refrigerated biscuit dough
- 1 cup pepperoni slices
- 2 cups shredded mozzarella cheese
- 1 1/2 cups pizza sauce
- 1 tbsp olive oil
- 1 tsp dried Italian seasoning
- 1/4 cup grated parmesan cheese
- 2 tbsp chopped (optional) fresh basil
The pizza stone or steel we’d bake this on → Best Pizza Stones and Steels for 2026: Top Picks + Buying Guide
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Equipment for this recipe
Tools this recipe's steps call for, with a link to each on Amazon.
Instructions
- Step 1: Preheat oven to 375°F. Lightly grease a 9x13-inch baking dish with 1 tablespoon olive oil.
- Step 2: Cut 16 ounces refrigerated biscuit dough into quarters and scatter evenly in the bottom of the prepared dish.
- Step 3: Pour 1 1/2 cups pizza sauce evenly over the biscuit pieces, then sprinkle 1 cup pepperoni slices on top.
- Step 4: Layer 2 cups shredded mozzarella cheese evenly over the pepperoni and biscuit mixture.
- Step 5: Sprinkle 1 teaspoon dried Italian seasoning and 1/4 cup grated parmesan cheese over the top.
- Step 6: Bake uncovered for 25-30 minutes until biscuits are cooked through and golden at the edges, and cheese is bubbly and slightly browned.
- Step 7: Let cool for 5 minutes, then sprinkle 2 tablespoons chopped fresh basil over before slicing and serving.








