Maple-Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

Tender pork tenderloin coated with a sweet and tangy maple mustard glaze paired with caramelized Brussels sprouts. This american-inspired pork ready in about 45 minutes pairs trimmed pork tenderloin, trimmed and halved Brussels sprouts, divided olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 380 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 30 min Serves 4 American cuisine 380 cal/serving
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Ingredients

Instructions

  1. Step 1: Preheat oven to 400°F. In a small bowl, whisk 3 tbsp Dijon mustard, 2 tbsp pure maple syrup, 1 tbsp apple cider vinegar, and 1/2 tsp garlic powder until smooth.
  2. Step 2: Rub 1 tsp salt and 1/2 tsp black pepper evenly over 1.5 lbs trimmed pork tenderloin. Brush the maple-mustard glaze all over the pork.
  3. Step 3: Toss 1 lb halved Brussels sprouts with 2 tbsp olive oil, 1/2 tsp salt, and 1/2 tsp black pepper in a bowl until coated.
  4. Step 4: Place the pork tenderloin in the center of a rimmed baking sheet and arrange the Brussels sprouts around it. Drizzle the remaining 1 tbsp olive oil over the sprouts.
  5. Step 5: Roast for 25-30 minutes, basting the pork with any glaze from the pan halfway through, until the internal temp of pork reaches 145°F and sprouts are caramelized.
  6. Step 6: Remove pork from oven, tent with foil and rest for 10 minutes before slicing. Serve alongside the roasted Brussels sprouts.

Equipment for this recipe

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Frequently asked questions

How long does Maple-Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts take to make?

Total time is about 45 minutes (15 min prep + 30 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Maple-Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep trimmed pork tenderloin from drying out.

Can I substitute ingredients in Maple-Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Maple-Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Maple-Mustard Glazed Pork Tenderloin with Roasted Brussels Sprouts?

American pork like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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