Mediterranean Sheet Pan Lemon-Oregano Salmon

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Oven-roasted salmon fillets with lemon, oregano, and a medley of roasted Mediterranean vegetables cooked on a single sheet pan. This mediterranean-inspired seafood (mediterranean) ready in about 28 minutes pairs (6 oz each) salmon fillets, lemon juice, olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 350 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 18 min Serves 4 Mediterranean cuisine 350 cal/serving
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Ingredients

Instructions

  1. Step 1: Preheat oven to 400°F. In a small bowl, whisk together 3 tbsp lemon juice, 1/4 cup olive oil, 2 tsp dried oregano, and 3 minced garlic cloves.
  2. Step 2: Place 4 salmon fillets skin-side down on one side of a large rimmed baking sheet. Arrange 1 sliced medium zucchini, 1 pint cherry tomatoes, and 1 small red onion cut into wedges on the other side.
  3. Step 3: Drizzle the lemon-oregano mixture evenly over the salmon and vegetables, then season everything with 1 tsp salt and 1/2 tsp black pepper.
  4. Step 4: Roast in the oven for 15-18 minutes until salmon is cooked through and vegetables are tender.
  5. Step 5: Remove from oven and sprinkle 2 tbsp chopped fresh parsley over the salmon and vegetables before serving.

Equipment for this recipe

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Frequently asked questions

How long does Mediterranean Sheet Pan Lemon-Oregano Salmon take to make?

Total time is about 28 minutes (10 min prep + 18 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Mediterranean Sheet Pan Lemon-Oregano Salmon?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep (6 oz each) salmon fillets from drying out.

Can I substitute ingredients in Mediterranean Sheet Pan Lemon-Oregano Salmon?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Mediterranean Sheet Pan Lemon-Oregano Salmon for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Mediterranean Sheet Pan Lemon-Oregano Salmon?

Mediterranean seafood like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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