Migraine-Relief Salmon with Avocado Spinach

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

A brain-boosting, anti-inflammatory dinner featuring omega-3-rich salmon and magnesium-packed spinach, perfect for easing Whole30-related headaches. This mediterranean-inspired whole30 (anti-inflammatory) ready in about 30 minutes pairs salmon fillets, large avocado, fresh spinach for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 450 calories and feeds 2, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

★ 4.1 (8 ratings) Prep: 15 min Cook: 15 min Serves 2 Mediterranean cuisine 450 cal/serving
Plan a meal with the AI → Shop this recipe on Instacart → Shop equipment ↓

Ingredients

Instructions

  1. Step 1: Preheat oven to 400°F. Pat 1 lb salmon fillets dry, then season with 1 tsp smoked paprika, 1/2 tsp garlic powder, and 1/4 tsp sea salt.
  2. Step 2: Heat 2 tbsp avocado oil in a skillet over medium-high heat until shimmering. Add salmon skin-side down and cook for 5 minutes until golden brown, then flip and bake in the preheated oven for 8-10 minutes until opaque and flaky.
  3. Step 3: While salmon cooks, slice 1 large avocado and place on a plate. Squeeze juice from 1 lemon over the avocado. Add 4 cups fresh spinach to the skillet and cook for 2 minutes until wilted and tender, stirring occasionally.

Equipment for this recipe

Top-rated tools to make this recipe successfully.

More Bakeware & baking tools → Shop all kitchen tools →

Frequently asked questions

How long does Migraine-Relief Salmon with Avocado Spinach take to make?

Total time is about 30 minutes (15 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Migraine-Relief Salmon with Avocado Spinach?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep salmon fillets from drying out.

Can I substitute ingredients in Migraine-Relief Salmon with Avocado Spinach?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Migraine-Relief Salmon with Avocado Spinach for a different number of people?

The recipe is written for 2 servings. Multiply each ingredient by (your serving target / 2). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Migraine-Relief Salmon with Avocado Spinach?

Mediterranean whole30 like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.