One-Pan Balsamic Beef and Brussels Sprouts Skillet

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Tender strips of beef seared and simmered with caramelized Brussels sprouts in a tangy balsamic glaze, all made in one skillet for an easy Whole30 meal. This american-inspired whole30 (whole30, gluten-free) ready in about 25 minutes pairs thinly sliced into strips sirloin steak, trimmed and halved Brussels sprouts, extra virgin olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 350 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 15 min Serves 4 American cuisine 350 cal/serving
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Ingredients

Instructions

  1. Step 1: Heat 2 tablespoons extra virgin olive oil in a large skillet over medium-high heat until shimmering. Add 1 pound halved Brussels sprouts cut-side down and cook without stirring for 5 minutes until deeply browned and caramelized.
  2. Step 2: Stir the Brussels sprouts and add 4 minced garlic cloves, cooking for 1 minute until fragrant. Remove the sprouts from the skillet and set aside.
  3. Step 3: Add the remaining 1 tablespoon extra virgin olive oil to the skillet and add 1 pound thinly sliced sirloin steak strips. Sear for 3-4 minutes until browned on all sides but still tender.
  4. Step 4: Return the Brussels sprouts to the skillet with the beef. Pour in 1/4 cup balsamic vinegar, 1 teaspoon sea salt, 1/2 teaspoon black pepper, and 1/4 teaspoon crushed red pepper flakes if using.
  5. Step 5: Simmer everything together for 2-3 minutes until the balsamic thickens slightly and coats the beef and sprouts. Serve hot.

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Frequently asked questions

How long does One-Pan Balsamic Beef and Brussels Sprouts Skillet take to make?

Total time is about 25 minutes (10 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover One-Pan Balsamic Beef and Brussels Sprouts Skillet?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep extra virgin olive oil from drying out.

Can I substitute ingredients in One-Pan Balsamic Beef and Brussels Sprouts Skillet?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale One-Pan Balsamic Beef and Brussels Sprouts Skillet for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

Is One-Pan Balsamic Beef and Brussels Sprouts Skillet whole30?

Yes — this recipe is tagged whole30, gluten-free based on its ingredient list. Always cross-check labels for packaged ingredients (sauces, broths, condiments) since formulations vary by brand.

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