Oven-Roasted Turkey Breast with Sage Butter

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

A succulent turkey breast roasted with a fragrant sage butter rub, perfect for a Thanksgiving centerpiece. This american-inspired thanksgiving ready in about 95 minutes pairs boneless turkey breast, unsalted butter, fresh sage leaves for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 350 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 80 min Serves 6 American cuisine 350 cal/serving
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Ingredients

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Instructions

  1. Step 1: Preheat the oven to 375°F. In a small bowl, combine 6 tablespoons unsalted butter, 2 tablespoons finely chopped fresh sage leaves, and 3 minced garlic cloves until well mixed.
  2. Step 2: Pat 4 pounds boneless turkey breast dry with paper towels. Rub the turkey breast all over with 1 tablespoon olive oil, then season evenly with 1 tablespoon kosher salt and 1 teaspoon black pepper.
  3. Step 3: Spread the sage butter mixture evenly over the entire surface of the turkey breast, pressing it slightly to adhere.
  4. Step 4: Place the turkey breast on a rack in a roasting pan. Roast in the preheated oven for about 1 hour 20 minutes, or until an instant-read thermometer inserted into the thickest part registers 160°F.
  5. Step 5: Remove the turkey breast from the oven and tent with foil. Let rest for 15 minutes before slicing to allow the juices to redistribute.

Frequently asked questions

How long does Oven-Roasted Turkey Breast with Sage Butter take to make?

Total time is about 95 minutes (15 min prep + 80 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Oven-Roasted Turkey Breast with Sage Butter?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep boneless turkey breast from drying out.

Can I substitute ingredients in Oven-Roasted Turkey Breast with Sage Butter?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Oven-Roasted Turkey Breast with Sage Butter for a different number of people?

The recipe is written for 6 servings. Multiply each ingredient by (your serving target / 6). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Oven-Roasted Turkey Breast with Sage Butter?

American thanksgiving like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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