Pan-Seared Catfish Po' Boy with Creole Remoulade

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

A classic New Orleans sandwich featuring crispy pan-seared catfish fillets nestled in a French baguette with a tangy Creole remoulade sauce and crisp lettuce. This louisiana creole-inspired sandwiches & wraps ready in about 25 minutes pairs catfish fillets, all-purpose flour, paprika for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 480 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 10 min Serves 4 Louisiana Creole cuisine 480 cal/serving
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Ingredients

Instructions

  1. Step 1: In a shallow bowl, combine 1 cup all-purpose flour, 1 tsp paprika, 1/2 tsp cayenne pepper, 1 tsp salt, and 1/2 tsp black pepper; mix well.
  2. Step 2: Pat dry 1 lb catfish fillets and dredge each piece in the seasoned flour mixture, shaking off excess.
  3. Step 3: Heat 1/4 cup vegetable oil in a large skillet over medium-high heat until shimmering, about 3 minutes.
  4. Step 4: Add the coated catfish fillets and cook for 4 minutes per side until golden brown and cooked through; remove and drain on paper towels.
  5. Step 5: Slice 1 French baguette lengthwise but not all the way through; toast lightly if desired.
  6. Step 6: Spread 1/2 cup Creole remoulade sauce evenly on the inside of the baguette.
  7. Step 7: Layer 4 romaine lettuce leaves and 4 tomato slices on the bottom half of the baguette.
  8. Step 8: Place the hot catfish fillets on top, close the sandwich, slice into portions, and serve immediately.

Equipment for this recipe

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Frequently asked questions

How long does Pan-Seared Catfish Po' Boy with Creole Remoulade take to make?

Total time is about 25 minutes (15 min prep + 10 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Pan-Seared Catfish Po' Boy with Creole Remoulade?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep catfish fillets from drying out.

Can I substitute ingredients in Pan-Seared Catfish Po' Boy with Creole Remoulade?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Pan-Seared Catfish Po' Boy with Creole Remoulade for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Pan-Seared Catfish Po' Boy with Creole Remoulade?

Louisiana Creole sandwiches & wraps like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.