Pan-Seared Salmon with Roasted Brussels Sprouts and Avocado Salsa

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · ·

A vibrant Whole30-compliant dish featuring crispy-skinned salmon paired with caramelized Brussels sprouts and a fresh avocado salsa to brighten each bite. This whole30-inspired whole30 (whole30, gluten free) ready in about 45 minutes blends 6 oz each salmon fillets, halved Brussels sprouts, large, diced avocado into a versatile sauce that lifts everything from grain bowls and roasted vegetables to grilled proteins — a small-batch staple worth keeping in the fridge. Each serving lands at about 420 calories and feeds 4, so a small batch covers several meals across the week without taking over the fridge. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 30 min Serves 4 Whole30 cuisine 420 cal/serving
Plan a meal with the AI → Shop this recipe on Instacart → Shop equipment ↓

Ingredients

Instructions

  1. Step 1: Preheat oven to 425°F. Toss 1 lb halved Brussels sprouts with 2 tbsp extra virgin olive oil, 1/2 tsp sea salt, and 1/4 tsp black pepper. Spread them on a baking sheet and roast for 20-25 minutes until edges are golden and sprouts are tender.
  2. Step 2: While sprouts roast, pat dry 4 salmon fillets (6 oz each) and season both sides with 1/2 tsp sea salt, 1/4 tsp black pepper, and 1/2 tsp paprika. Heat 2 tbsp olive oil in a large skillet over medium-high heat.
  3. Step 3: Place salmon fillets skin-side down in the hot skillet and cook for 4-5 minutes until skin is crisp. Flip and cook an additional 3-4 minutes until salmon is opaque and flakes easily.
  4. Step 4: In a bowl, combine 1 diced large avocado, 1 cup halved cherry tomatoes, 1/4 cup finely diced red onion, 2 tbsp chopped fresh cilantro, 2 tbsp lime juice, and 1 minced garlic clove. Gently toss to combine and season with a pinch of sea salt.
  5. Step 5: Plate the salmon alongside the roasted Brussels sprouts and top with a generous spoonful of the avocado salsa. Serve immediately.

Equipment for this recipe

Top-rated tools to make this recipe successfully.

More Bakeware & baking tools → Shop all kitchen tools →

Frequently asked questions

How long does Pan-Seared Salmon with Roasted Brussels Sprouts and Avocado Salsa take to make?

Total time is about 45 minutes (15 min prep + 30 min cook). A small batch typically covers several meals in the week — store as the recipe directs.

How do I store leftover Pan-Seared Salmon with Roasted Brussels Sprouts and Avocado Salsa?

Transfer to an airtight jar and refrigerate for up to 5–7 days. Most sauces freeze well for up to 2 months — portion into small containers or freezer bags so you can thaw only what you need. Stir before serving; cream- or yogurt-based sauces may separate on standing.

Can I substitute ingredients in Pan-Seared Salmon with Roasted Brussels Sprouts and Avocado Salsa?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Pan-Seared Salmon with Roasted Brussels Sprouts and Avocado Salsa for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

Is Pan-Seared Salmon with Roasted Brussels Sprouts and Avocado Salsa whole30?

Yes — this recipe is tagged whole30, gluten free, paleo based on its ingredient list. Always cross-check labels for packaged ingredients (sauces, broths, condiments) since formulations vary by brand.

Related recipes