Pan-Seared Salmon with Roasted Brussels Sprouts and Lemon-Garlic Sauce

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Tender pan-seared salmon fillets served alongside caramelized roasted Brussels sprouts, finished with a bright lemon-garlic sauce. This mediterranean-inspired whole30 (gluten free) ready in about 40 minutes pairs salmon fillets, Brussels sprouts, extra virgin olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 380 calories and feeds 4, so it slots cleanly into a Whole30 week and pairs well with roasted sweet potato or a simple olive-oil salad. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 30 min Serves 4 Mediterranean cuisine 380 cal/serving
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Ingredients

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Instructions

  1. Step 1: Preheat oven to 425°F. Toss 1 lb halved Brussels sprouts with 2 tbsp extra virgin olive oil, 1/2 tsp sea salt, and 1/4 tsp black pepper; spread on a baking sheet and roast for 20-25 minutes until tender and caramelized.
  2. Step 2: Meanwhile, heat 1 tbsp extra virgin olive oil in a large skillet over medium-high heat. Season 4 salmon fillets with 1/2 tsp sea salt and 1/4 tsp black pepper. Place salmon skin-side down and cook for 4-5 minutes until crispy, then flip and cook an additional 3-4 minutes until cooked through.
  3. Step 3: In a small bowl, combine 4 minced garlic cloves and 2 tbsp lemon juice. Remove skillet from heat and swirl the garlic-lemon mixture into the pan juices to create a sauce.
  4. Step 4: Plate salmon with roasted Brussels sprouts and drizzle the lemon-garlic sauce over the top. Garnish with 2 tbsp chopped fresh parsley before serving.

Frequently asked questions

How long does Pan-Seared Salmon with Roasted Brussels Sprouts and Lemon-Garlic Sauce take to make?

Total time is about 40 minutes (10 min prep + 30 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Pan-Seared Salmon with Roasted Brussels Sprouts and Lemon-Garlic Sauce?

Refrigerate in a covered airtight container for up to 3–4 days (FDA FoodKeeper guideline for cooked fish). Store any fresh salsa or citrus-based garnish in a separate container — it keeps for up to 2 days. Freeze cooked fish (without fresh garnishes) for up to 3 months; thaw overnight in the fridge and reheat gently at 275°F until just warmed through to preserve texture.

Can I substitute ingredients in Pan-Seared Salmon with Roasted Brussels Sprouts and Lemon-Garlic Sauce?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Pan-Seared Salmon with Roasted Brussels Sprouts and Lemon-Garlic Sauce for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

Is Pan-Seared Salmon with Roasted Brussels Sprouts and Lemon-Garlic Sauce whole30?

Yes — this recipe is tagged whole30, gluten free, paleo based on its ingredient list. Always cross-check labels for packaged ingredients (sauces, broths, condiments) since formulations vary by brand.

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