Sautéed Pork Tenderloin Medallions with Mushrooms and Garlic

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Tender pork tenderloin medallions cooked with earthy mushrooms and garlic in a skillet, making a flavorful Whole30-compliant dinner. This american-inspired pork (whole30, gluten free) ready in about 30 minutes pairs sliced cremini mushrooms, minced garlic cloves, extra virgin olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 330 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 20 min Serves 4 American cuisine 330 cal/serving
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Ingredients

Instructions

  1. Step 1: Heat 2 tbsp extra virgin olive oil in a large skillet over medium-high heat until shimmering. Season 1 lb pork tenderloin medallions with 1/2 tsp sea salt and 1/4 tsp black pepper. Add pork to skillet and sear for 3-4 minutes per side until golden brown and cooked through. Remove pork and set aside.
  2. Step 2: Lower heat to medium, add 1 tbsp extra virgin olive oil to the skillet. Add 8 oz sliced cremini mushrooms and sauté for 5 minutes until browned and moisture evaporates.
  3. Step 3: Add 4 minced garlic cloves and 1 tbsp fresh thyme leaves to the mushrooms, cooking for 1 minute until fragrant.
  4. Step 4: Pour in 1/4 cup chicken broth and stir, scraping browned bits from the pan. Let sauce simmer for 2-3 minutes until slightly reduced.
  5. Step 5: Return pork medallions to skillet and toss gently with mushrooms and sauce to rewarm. Adjust seasoning with remaining 1/2 tsp sea salt and 1/4 tsp black pepper if needed. Serve hot.

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Frequently asked questions

How long does Sautéed Pork Tenderloin Medallions with Mushrooms and Garlic take to make?

Total time is about 30 minutes (10 min prep + 20 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Sautéed Pork Tenderloin Medallions with Mushrooms and Garlic?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep sliced cremini mushrooms from drying out.

Can I substitute ingredients in Sautéed Pork Tenderloin Medallions with Mushrooms and Garlic?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Sautéed Pork Tenderloin Medallions with Mushrooms and Garlic for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

Is Sautéed Pork Tenderloin Medallions with Mushrooms and Garlic whole30?

Yes — this recipe is tagged whole30, gluten free, dairy free, paleo, high protein based on its ingredient list. Always cross-check labels for packaged ingredients (sauces, broths, condiments) since formulations vary by brand.

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