Sheet Pan Cajun-Spiced Catfish with Roasted Sweet Potato Wedges

By AislePrompt Editorial · Published 2026-05-30 · Updated 2026-05-30

How this recipe was made — this recipe was drafted by AislePrompt's AI-assisted pipeline from technique templates and USDA-sourced nutrition data, and published by AislePrompt Editorial — see how AislePrompt recipes are drafted and published.

This sheet pan dish features tender catfish fillets seasoned with bold Cajun spices alongside caramelized sweet potato wedges for a hearty Southern-inspired meal. This Southern-inspired seafood recipe, ready in about 50 minutes, pairs catfish fillets, sweet potatoes, olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 320 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 15 min Cook: 35 min Serves 4 Southern cuisine 320 cal/serving

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Ingredients

4 pieces, about 6 oz each catfish fillets
2 medium, peeled and cut into 1/2-inch wedges sweet potatoes
3 tbsp olive oil
2 tbsp Cajun seasoning
1 tsp garlic powder
1 tsp smoked paprika
1 tsp salt
1/2 tsp black pepper
for serving lemon wedges

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Instructions

Step 1: Preheat oven to 425°F. Toss 2 medium peeled sweet potatoes cut into 1/2-inch wedges with 2 tbsp olive oil, 1 tsp salt, and 1/2 tsp black pepper on a large rimmed baking sheet. Spread in a single layer and roast for 20 minutes until starting to soften and caramelize.
Step 2: Meanwhile, in a small bowl combine 2 tbsp Cajun seasoning, 1 tsp garlic powder, and 1 tsp smoked paprika. Pat dry 4 catfish fillets (6 oz each) and brush with remaining 1 tbsp olive oil. Sprinkle the Cajun spice mix evenly over both sides of the fillets.
Step 3: After the sweet potatoes have roasted 20 minutes, move them to one side of the pan and place the catfish fillets on the other side. Roast everything together for an additional 12-15 minutes until the catfish flakes easily with a fork and sweet potatoes are tender and browned at the edges.
Step 4: Serve the catfish and sweet potatoes immediately with fresh lemon wedges for squeezing over the top.