Slow-Roasted Beef Brisket with Gulfport BBQ Glaze

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Tender, slow-roasted beef brisket finished with a sweet and smoky Gulfport-style BBQ glaze that highlights Southern flavors. This american southern-inspired beef ready in about 320 minutes pairs Beef brisket, Brown sugar, Smoked paprika for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 450 calories and feeds 6, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 20 min Cook: 300 min Serves 6 American Southern cuisine 450 cal/serving
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Ingredients

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Instructions

  1. Step 1: Preheat oven to 275°F. Combine 2 tbsp brown sugar, 1 tbsp smoked paprika, 1 tsp garlic powder, 1 tsp onion powder, 1 tbsp salt, and 1 tsp black pepper in a small bowl. Rub this spice mix evenly over all sides of the 3 lb beef brisket.
  2. Step 2: Heat 2 tbsp olive oil in a large oven-safe skillet over medium-high heat. Sear the brisket for 4-5 minutes per side until a deep brown crust forms.
  3. Step 3: In a separate bowl, whisk together 1/4 cup apple cider vinegar, 1/2 cup ketchup, 2 tbsp honey, and 1 tbsp Worcestershire sauce to create the BBQ glaze.
  4. Step 4: Pour half of the BBQ glaze over the brisket, cover the skillet tightly with foil, and roast in the oven for 4-5 hours until the brisket is fork-tender.
  5. Step 5: Every hour, baste the brisket with remaining glaze. Once done, let rest for 15 minutes before slicing against the grain and serving with extra glaze.

Frequently asked questions

How long does Slow-Roasted Beef Brisket with Gulfport BBQ Glaze take to make?

Total time is about 320 minutes (20 min prep + 300 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Slow-Roasted Beef Brisket with Gulfport BBQ Glaze?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep beef brisket from drying out.

Can I substitute ingredients in Slow-Roasted Beef Brisket with Gulfport BBQ Glaze?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Slow-Roasted Beef Brisket with Gulfport BBQ Glaze for a different number of people?

The recipe is written for 6 servings. Multiply each ingredient by (your serving target / 6). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Slow-Roasted Beef Brisket with Gulfport BBQ Glaze?

American Southern beef like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.