Cheese and Spinach Stuffed Chicken Breast with Garlic Butter Sauce

By AislePrompt Test Kitchen · Reviewed by AislePrompt Editorial · Published 2026-05-09 · Updated 2026-05-09

Tender chicken breasts filled with creamy cheese and spinach, pan-seared and finished with a fragrant garlic butter sauce for a rich keto entree. This american-inspired keto (keto, low carb) ready in about 40 minutes blends packed fresh spinach, softened cream cheese, shredded mozzarella cheese into a versatile sauce that lifts everything from grain bowls and roasted vegetables to grilled proteins — a small-batch staple worth keeping in the fridge. Each serving lands at about 450 calories and feeds 4, so a small batch covers several meals across the week without taking over the fridge. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Ingredients

• 4 boneless, skinless, about 6 oz each chicken breasts
• 2 cups packed fresh spinach
• 4 oz softened cream cheese
• 1/2 cup shredded mozzarella cheese
• 4 minced garlic cloves
• 4 tbsp unsalted butter
• 2 tbsp olive oil
• 1 tsp salt
• 1/2 tsp black pepper
• 1/2 tsp dried oregano

Instructions

1. Step 1: Preheat oven to 375°F. Using a sharp knife, cut a horizontal pocket into each of the 4 chicken breasts without cutting all the way through.
2. Step 2: In a medium skillet over medium heat, add 1 tbsp olive oil and sauté 2 cups fresh spinach for 2-3 minutes until wilted. Remove from heat and let cool slightly.
3. Step 3: In a bowl, mix the sautéed spinach, 4 oz softened cream cheese, and 1/2 cup shredded mozzarella cheese until combined.
4. Step 4: Stuff each chicken breast pocket evenly with the cheese and spinach mixture. Secure with toothpicks if needed.
5. Step 5: Season the stuffed chicken breasts with 1 tsp salt, 1/2 tsp black pepper, and 1/2 tsp dried oregano.
6. Step 6: Heat remaining 1 tbsp olive oil and 2 tbsp unsalted butter in an oven-safe skillet over medium-high heat. Add chicken breasts and sear for 3-4 minutes per side until golden brown.
7. Step 7: Transfer the skillet to the oven and bake for 15-18 minutes until the chicken is cooked through (internal temperature 165°F).
8. Step 8: Meanwhile, melt the remaining 2 tbsp butter in a small pan over low heat, add 4 minced garlic cloves, and cook for 2 minutes until fragrant. Drizzle this garlic butter sauce over the finished chicken before serving.